SCHEMBL760070

SCHEMBL760070

COc1ccc(-c2ccccc2I)cc1.Cc1ccc(S(=O)(=O)O)cc1

nearest known ligand 0.44

Known targets — ChEMBL curated mechanism

ABL1BMXBRAFBTKCHRNA4CHRNB2CSNK1EEGFRERBB2F10FLT1FLT3FLT4IGF1RINSRITKJAK3KDRKITOPRM1PARP1PARP2PDGFRBPIK3CDRAF1RETSLC18A2TECTXKdacAdacBdacCftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABL1 known ✓ P00519 1/20 0.41
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
PTGS2 P35354 2/20 0.44
HDAC4 P56524 1/20 0.43
HDAC2 Q92769 1/20 0.43
HDAC8 Q9BY41 1/20 0.43
LMNA P02545 4/20 0.43
ALDH1A1 P00352 4/20 0.43
STAT3 P40763 3/20 0.43
NPSR1 Q6W5P4 1/20 0.43
MAPT P10636 3/20 0.43
PTGS1 P23219 1/20 0.42
ABCB1 P08183 1/20 0.41
BCR P11274 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
KDM4E B2RXH2 1/20 0.41
HTT P42858 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4655793 0.91 HDAC4 (0.47) MEN1KMT2APTGS2HDAC4HDAC2
SCHEMBL10492054 0.90 LMNA (0.48) MEN1KMT2APTGS2LMNAALDH1A1
SCHEMBL1140939 0.86 ALDH1A1 (0.39) MEN1KMT2APTGS2LMNAALDH1A1
SCHEMBL218886 0.86 ALDH1A1 (0.39) MEN1KMT2APTGS2LMNAALDH1A1
SCHEMBL4655811 0.85 TP53 (0.48) KMT2APTGS2HDAC4HDAC2HDAC8
SCHEMBL7741653 0.85 LTA4H (0.50) MEN1KMT2APTGS2LMNAALDH1A1
SCHEMBL7739971 0.85 PDE4A (0.42) MEN1KMT2APTGS2HDAC4HDAC2
SCHEMBL7574616 0.84 HDAC4 (0.51) MEN1KMT2APTGS2HDAC4HDAC2
SCHEMBL7892661 0.84 TSHR (0.44) LMNAALDH1A1NPSR1MAPTSMN1; SMN2
SCHEMBL7172569 0.82 CNR2 (0.40) MEN1KMT2APTGS2LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240352203-A1 FILM-FORMING MATERIAL FOR SEMICONDUCTOR, MEMBER-FORMING MATERIAL FOR SEMICONDUCTOR, PROCESS MEMBER-FORMING MATERIAL FOR SEMICONDUCTOR, UNDERLAYER FILM-FORMING MATERIAL, UNDERLAYER FILM, AND SEMICONDUCTOR DEVICE ADEKA CORPORATION (JP) 2024-10-24 US disclosed
EP-4375750-A1 FILM-FORMING MATERIAL FOR SEMICONDUCTOR, MEMBER-FORMING MATERIAL FOR SEMICONDUCTOR, PROCESS MEMBER-FORMING MATERIAL FOR SEMICONDUCTOR, UNDERLAYER FILM-FORMING MATERIAL, UNDERLAYER FILM, AND SEMICONDUCTOR DEVICE ADEKA CORPORATION (JP) 2024-05-29 EP disclosed
CN-115551923-A Polysulfonamide polymers, positive photosensitive compositions containing them and their use 崔国英 2022-12-30 CN disclosed
CN-115433358-A Polyamide-b-amic acid polymers, positive photosensitive compositions and their use 山东圣泉新材料股份有限公司 2022-12-06 CN disclosed
US-11450445-B2 Electroconductive film and method for manufacturing electroconductive pattern TOKYO UNIVERSITY OF SCIENCE FOUNDATION (JP) 2022-09-20 US disclosed
CN-107003608-B Photopatternable composition and method for manufacturing transistor device by using same 飞利斯有限公司 2020-09-25 CN disclosed
US-20200303086-A1 ELECTROCONDUCTIVE FILM AND METHOD FOR MANUFACTURING ELECTROCONDUCTIVE PATTERN TOKYO UNIVERSITY OF SCIENCE FOUNDATION (JP) 2020-09-24 US disclosed
CN-111647160-A Aromatic polyamide sulfonamide polymer, positive photosensitive composition containing aromatic polyamide sulfonamide polymer, and use thereof 崔国英 2020-09-11 CN disclosed
CN-111548496-A Polysulfonamide polymers, low-temperature crosslinked positive-working photosensitive compositions containing polysulfonamide polymers and use thereof 崔国英 2020-08-18 CN disclosed
US-10720259-B2 Electroconductive film and method for manufacturing electroconductive pattern TOKYO UNIVERSITY OF SCIENCE FOUNDATION (JP) 2020-07-21 US disclosed
US-20020172873-A1 Photosensitive resin composition, color filter, and copolymer resin useful for them DAI NIPPON PRINTING CO., LTD. (JP) 2002-11-21 US disclosed
US-6410206-B1 MIXTURE OF (METH)ACRYLIC ACID, ACRYLATED ESTER AND EPOXYCOMPOUND DAI NIPPON PRINTING CO., LTD. (JP) 2002-06-25 US disclosed
EP-1193553-A2 Exposure method, exposure apparatus, x-ray mask, semiconductor device and microstructure MITSUBISHI DENKI KABUSHIKI KAISHA (JP) 2002-04-03 EP disclosed
EP-0880075-B1 Radiation sensitive resin composition JSR CORP (JP) 2001-10-17 EP disclosed
EP-1035439-A2 Photosensitive resin composition, color filter, and copolymer resin useful for them DAI NIPPON PRINTING CO., LTD. (JP) 2000-09-13 EP disclosed
US-5958648-A Radiation sensitive resin composition JSR CORPORATION (JP) 1999-09-28 US disclosed
EP-0880075-A1 Radiation sensitive resin composition JSR Corporation (JP) 1998-11-25 EP disclosed
EP-0594452-B1 Radiation sensitive resin composition for microlens JAPAN SYNTHETIC RUBBER CO LTD (JP) 1997-01-15 EP disclosed
US-5432039-A Radiation sensitive quinone diazide and resin composition for microlens JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1995-07-11 US disclosed
EP-0594452-A2 Radiation sensitive resin composition for microlens JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1994-04-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240352203-A1 FILM-FORMING MATERIAL FOR SEMICONDUCTOR, MEMBER-FORMING MATERIAL FOR SEMICONDUCTOR, PROCESS MEMBER-FORMING MATERIAL FOR SEMICONDUCTOR, UNDERLAYER FILM-FORMING MATERIAL, UNDERLAYER FILM, AND SEMICONDUCTOR DEVICE FBXL19, SRSF9, CNOT9 ABL1 1226/4885MEN1 795/4885KMT2A 1297/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.