SCHEMBL7602896

SCHEMBL7602896

C[SiH](c1ccccc1)[Ti](C)(C)(C1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 4/20 0.31
BRD4 O60885 1/20 0.31
CCL2 P13500 1/20 0.31
HTR6 P50406 1/20 0.30
HTR2A P28223 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7600844 0.85 SIGMAR1 (0.32) SIGMAR1BRD4CCL2HTR6HTR2A
SCHEMBL7601265 0.83 BRD4 (0.34) SIGMAR1BRD4CCL2HTR6HTR2A
SCHEMBL8605230 0.83 SIGMAR1 (0.31) SIGMAR1BRD4CCL2
SCHEMBL797002 0.76 SIGMAR1 (0.31) SIGMAR1
SCHEMBL7633085 0.75 HTR2A (0.34) SIGMAR1BRD4CCL2HTR6HTR2A
SCHEMBL7924385 0.75 GPR3 (0.30)
SCHEMBL8606772 0.75 BRD4 (0.33) SIGMAR1BRD4CCL2HTR6HTR2A
SCHEMBL7628486 0.72 SIGMAR1 (0.32) SIGMAR1BRD4CCL2HTR6HTR2A
SCHEMBL6469715 0.72 HTR6 (0.31) HTR6HTR2A
SCHEMBL2534262 0.72 BRD4 (0.36) SIGMAR1BRD4CCL2HTR6HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6410665-B1 POLYMERIZATION COORDINATION CATALYST FOR ALPHA-OLEFIN BASELL POLYOLEFINE GMBH (DE) 2002-06-25 US claimed
US-6410665-B1 POLYMERIZATION COORDINATION CATALYST FOR ALPHA-OLEFIN BASELL POLYOLEFINE GMBH (DE) 2002-06-25 US disclosed