Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | STS | P08842 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7604333 | 0.92 | MAPT (0.46) | MAPTKMT2ALMNATSHRCYP1A2 | |
| SCHEMBL9006593 | 0.81 | THRB (0.46) | MAPTKMT2ALMNATSHRCYP1A2 | |
| SCHEMBL9006412 | 0.80 | TDP1 (0.48) | MAPTKMT2ALMNATSHRCYP1A2 | |
| SCHEMBL9172361 | 0.76 | CA1 (0.60) | MAPTKMT2ATSHRALDH1A1TDP1 | |
| SCHEMBL9906997 | 0.76 | MAPT (0.38) | MAPTKMT2ALMNATSHRCYP1A2 | |
| SCHEMBL29168514 | 0.75 | ESR1 (0.67) | MAPTKMT2ALMNATSHRCYP1A2 | |
| SCHEMBL5309873 | 0.75 | ELANE (0.52) | MAPTKMT2ALMNAMAPK1STS | |
| SCHEMBL7601244 | 0.75 | LMNA (0.41) | MAPTKMT2ALMNATSHRCYP1A2 | |
| SCHEMBL13422469 | 0.75 | PARP10 (0.59) | MAPTKMT2ASMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL4062238 | 0.73 | HSD17B10 (0.53) | KMT2ALMNATSHRALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8183325-B2 | Mixture of polyoxyalkylene radical, polysiloxane radicals and perfluorocyclobutane radical; medical equipment; contact lenses | BAUSCH & LOMB INCORPORATED (US) | 2012-05-22 | — | — | US | disclosed |
| US-7534836-B2 | Polysiloxanes including cyclic polymers , polyethers, polyethersiloxanes with crosslinkable end groups including a dimerizable perfluorovinylphenyl group; polyperfluorocyclobutanes; contact/intraocular lenses; oxygen permeability; wettability' biocompatability; quality; prolonged eye contact | BAUSCH & LOMB INCORPORATED (US) | 2009-05-19 | — | — | US | disclosed |
| US-7402634-B2 | Perfluorocyclobutane copolymers | BAUSCH AND LAMB INCORPORATED (US) | 2008-07-22 | — | — | US | disclosed |
| US-20070004886-A1 | Biomedical devices | BAUSCH & LOMB INCORPORATED | 2007-01-04 | — | — | US | disclosed |