Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | ESR1 | P03372 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7601249 | 0.92 | MAPT (0.43) | MAPTKMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL9006593 | 0.88 | THRB (0.46) | MAPTKMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL9006412 | 0.87 | TDP1 (0.48) | MAPTKMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL9906997 | 0.83 | MAPT (0.38) | MAPTKMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL7601244 | 0.82 | LMNA (0.41) | MAPTKMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL9172361 | 0.80 | CA1 (0.60) | MAPTKMT2ARAB9ATSHRALDH1A1 | |
| SCHEMBL5309873 | 0.79 | ELANE (0.52) | MAPTKMT2ANPC1RAB9ALMNA | |
| SCHEMBL13422469 | 0.79 | PARP10 (0.59) | MAPTKMT2ASMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL4062238 | 0.77 | HSD17B10 (0.53) | KMT2ATSHRLMNAALDH1A1TDP1 | |
| SCHEMBL9006488 | 0.76 | MAPT (0.57) | MAPTKMT2ASMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8198375-B2 | Trifluorovinyl aromatic containing poly(alkyl ether) prepolymers | BAUSCH & LOMB INCORPORATED (US) | 2012-06-12 | — | — | US | disclosed |
| US-8183325-B2 | Mixture of polyoxyalkylene radical, polysiloxane radicals and perfluorocyclobutane radical; medical equipment; contact lenses | BAUSCH & LOMB INCORPORATED (US) | 2012-05-22 | — | — | US | disclosed |
| US-7582704-B2 | Biomedical devices | BAUSCH & LOMB INCORPORATED (US) | 2009-09-01 | — | — | US | disclosed |
| US-20090192263-A1 | TRIFLUOROVINYL AROMATIC CONTAINING POLY(ALKYL ETHER) PREPOLYMERS | BAUSCH & LOMB MEXICO, S.A. DE C.V. (MX) | 2009-07-30 | — | — | US | disclosed |
| US-7544751-B2 | Polymerization products and biomedical devices containing same | BAUSCH & LOMB INCORPORATED (US) | 2009-06-09 | — | — | US | disclosed |
| US-7538160-B2 | Trifluorovinyl aromatic containing poly(alkyl ether) prepolymers | BAUSCH & LOMB INCORPORATED (US) | 2009-05-26 | — | — | US | disclosed |
| US-7534836-B2 | Polysiloxanes including cyclic polymers , polyethers, polyethersiloxanes with crosslinkable end groups including a dimerizable perfluorovinylphenyl group; polyperfluorocyclobutanes; contact/intraocular lenses; oxygen permeability; wettability' biocompatability; quality; prolonged eye contact | BAUSCH & LOMB INCORPORATED (US) | 2009-05-19 | — | — | US | disclosed |
| US-20080287626-A1 | Polymerization Products and Biomedical Devices Containing Same | PRZEDSIEBIORSTWO FARMACEUTYCZNE JELFA SPOLKA AKCYJNA (A/K/A PRZEDSIEBIORSTWO FARMACEUTYCZNE JELFA S.A.) (PL) | 2008-11-20 | — | — | US | disclosed |
| US-20080234454-A1 | PERFLUOROCYCLOBUTANE COPOLYMERS | PRZEDSIEBIORSTWO FARMACEUTYCZNE JELFA SPOLKA AKCYJNA (A/K/A PRZEDSIEBIORSTWO FARMACEUTYCZNE JELFA S.A.) (PL) | 2008-09-25 | — | — | US | disclosed |
| US-7425600-B2 | Polymerization products and biomedical devices containing same | BAUSCH & LOMB INCORPORATED (US) | 2008-09-16 | — | — | US | disclosed |
| US-7402634-B2 | Perfluorocyclobutane copolymers | BAUSCH AND LAMB INCORPORATED (US) | 2008-07-22 | — | — | US | disclosed |
| US-20070004897-A1 | Trifluorovinyl aromatic containing poly(alkyl ether) prepolymers | BAUSCH & LOMB INCORPORATED | 2007-01-04 | — | — | US | disclosed |
| US-20070004866-A1 | Biomedical devices | BAUSCH & LOMB INCORPORATED | 2007-01-04 | — | — | US | disclosed |
| US-20070004897-A1 | Trifluorovinyl aromatic containing poly(alkyl ether) prepolymers | BAUSCH & LOMB INCORPORATED | 2007-01-04 | — | — | US | disclosed |
| US-20070004867-A1 | Perfluorocyclobutane copolymers | BAUSCH & LOMB INCORPORATED | 2007-01-04 | — | — | US | disclosed |
| US-20070004868-A1 | Polymerization products and biomedical devices containing same | BAUSCH & LOMB INCORPORATED | 2007-01-04 | — | — | US | disclosed |
| US-20070004868-A1 | Polymerization products and biomedical devices containing same | BAUSCH & LOMB INCORPORATED | 2007-01-04 | — | — | US | disclosed |
| US-20070004886-A1 | Biomedical devices | BAUSCH & LOMB INCORPORATED | 2007-01-04 | — | — | US | disclosed |