Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7601244 | 0.84 | LMNA (0.41) | MAPTKMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL7604333 | 0.83 | MAPT (0.46) | MAPTKMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL1188371 | 0.77 | LMNA (0.51) | KMT2ASMN1; SMN2NPC1RAB9ATSHR | |
| SCHEMBL7601249 | 0.76 | MAPT (0.43) | MAPTKMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL9006412 | 0.74 | TDP1 (0.48) | MAPTKMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL9006593 | 0.73 | THRB (0.46) | MAPTKMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL21733186 | 0.70 | ALDH1A1 (0.57) | MAPTKMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL9172361 | 0.69 | CA1 (0.60) | MAPTKMT2ARAB9ATSHRALDH1A1 | |
| SCHEMBL12591552 | 0.69 | ALDH1A1 (0.44) | MAPTSMN1; SMN2TSHRLMNAMAPK1 | |
| SCHEMBL12267623 | 0.68 | TSHR (0.41) | MAPTKMT2ATSHRESR1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8198375-B2 | Trifluorovinyl aromatic containing poly(alkyl ether) prepolymers | BAUSCH & LOMB INCORPORATED (US) | 2012-06-12 | — | — | US | disclosed |
| US-7582704-B2 | Biomedical devices | BAUSCH & LOMB INCORPORATED (US) | 2009-09-01 | — | — | US | disclosed |
| US-20090192263-A1 | TRIFLUOROVINYL AROMATIC CONTAINING POLY(ALKYL ETHER) PREPOLYMERS | BAUSCH & LOMB MEXICO, S.A. DE C.V. (MX) | 2009-07-30 | — | — | US | disclosed |
| US-7544751-B2 | Polymerization products and biomedical devices containing same | BAUSCH & LOMB INCORPORATED (US) | 2009-06-09 | — | — | US | disclosed |
| US-7538160-B2 | Trifluorovinyl aromatic containing poly(alkyl ether) prepolymers | BAUSCH & LOMB INCORPORATED (US) | 2009-05-26 | — | — | US | disclosed |
| US-20080287626-A1 | Polymerization Products and Biomedical Devices Containing Same | PRZEDSIEBIORSTWO FARMACEUTYCZNE JELFA SPOLKA AKCYJNA (A/K/A PRZEDSIEBIORSTWO FARMACEUTYCZNE JELFA S.A.) (PL) | 2008-11-20 | — | — | US | disclosed |
| US-7425600-B2 | Polymerization products and biomedical devices containing same | BAUSCH & LOMB INCORPORATED (US) | 2008-09-16 | — | — | US | disclosed |
| US-7402634-B2 | Perfluorocyclobutane copolymers | BAUSCH AND LAMB INCORPORATED (US) | 2008-07-22 | — | — | US | disclosed |
| US-20070004897-A1 | Trifluorovinyl aromatic containing poly(alkyl ether) prepolymers | BAUSCH & LOMB INCORPORATED | 2007-01-04 | — | — | US | disclosed |
| US-20070004866-A1 | Biomedical devices | BAUSCH & LOMB INCORPORATED | 2007-01-04 | — | — | US | disclosed |
| US-20070004867-A1 | Perfluorocyclobutane copolymers | BAUSCH & LOMB INCORPORATED | 2007-01-04 | — | — | US | disclosed |
| US-20070004868-A1 | Polymerization products and biomedical devices containing same | BAUSCH & LOMB INCORPORATED | 2007-01-04 | — | — | US | disclosed |