Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 | P30411 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | C3AR1 | Q16581 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7606111 | 0.90 | KMT2A (0.47) | BDKRB2KMT2APDE4BPDE3ATP53 | |
| SCHEMBL13660764 | 0.82 | TP53 (0.48) | BDKRB2KMT2APDE4BPDE3ATP53 | |
| SCHEMBL7602899 | 0.81 | LMNA (0.50) | BDKRB2KMT2ATP53PGRLMNA | |
| SCHEMBL1178312 | 0.79 | BDKRB2 (0.37) | BDKRB2KMT2APDE4BPDE4APDE4C | |
| SCHEMBL1178782 | 0.77 | BDKRB2 (0.40) | BDKRB2KMT2ATP53 | |
| SCHEMBL7604032 | 0.77 | PGR (0.42) | BDKRB2KMT2APDE4BPDE3ATP53 | |
| Bicarbonate SCHEMBL3693843 | 0.76 | BDKRB2 (0.41) | BDKRB2TP53C3AR1 | |
| SCHEMBL1178491 | 0.73 | MCHR1 (0.41) | BDKRB2PDE4BMCHR1PDE4APDE4C | |
| SCHEMBL1177737 | 0.73 | MCHR1 (0.41) | BDKRB2KMT2APDE4BMCHR1PDE4A | |
| SCHEMBL7601926 | 0.73 | BDKRB2 (0.40) | BDKRB2KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268625-B1 | OXO-HETEROCYCLIC SUBSTITUTED CARBOXYLIC ACID DERIVATES AND THE USE THEREOF | Bayer Pharma AG (DE) | 2012-05-16 | — | — | EP | disclosed |