Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13660764 | 0.92 | TP53 (0.48) | KMT2ATP53LMNAPGRPOLB | |
| SCHEMBL7602899 | 0.90 | LMNA (0.50) | KMT2ATP53LMNAPGRPOLB | |
| SCHEMBL7601937 | 0.90 | BDKRB2 (0.37) | KMT2ATP53LMNAPGRHRH3 | |
| SCHEMBL7604032 | 0.83 | PGR (0.42) | KMT2ATP53LMNAPGRPDE4A | |
| SCHEMBL7601099 | 0.80 | KMT2A (0.45) | KMT2ATP53LMNAPGRPOLB | |
| SCHEMBL13660621 | 0.80 | KMT2A (0.55) | KMT2ATP53LMNAPGRHRH3 | |
| SCHEMBL7605776 | 0.80 | KMT2A (0.47) | KMT2ATP53LMNAPGRPOLB | |
| SCHEMBL7604168 | 0.79 | KMT2A (0.48) | KMT2ATP53LMNAPGRPOLB | |
| SCHEMBL7603999 | 0.79 | KMT2A (0.51) | KMT2ATP53PGRPOLBHRH3 | |
| SCHEMBL7601792 | 0.79 | KMT2A (0.51) | KMT2ATP53PGRPOLBHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268625-B1 | OXO-HETEROCYCLIC SUBSTITUTED CARBOXYLIC ACID DERIVATES AND THE USE THEREOF | Bayer Pharma AG (DE) | 2012-05-16 | — | — | EP | disclosed |