SCHEMBL760252

SCHEMBL760252

CCOc1ccc(I)cc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 1/20 0.74
TSHR P16473 1/20 0.58
TDP1 Q9NUW8 1/20 0.58
APP P05067 8/20 0.56
LTA4H P09960 2/20 0.54
KDM4E B2RXH2 2/20 0.48
ALDH1A1 P00352 2/20 0.48
PARP10 Q53GL7 1/20 0.48
RELA Q04206 1/20 0.48
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA7 P43166 1/20 0.48
CA9 Q16790 1/20 0.48
PRSS1 P07477 1/20 0.48
PRSS2 P07478 1/20 0.48
PRSS3 P35030 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
ADRA2A P08913 1/20 0.47
MAPT P10636 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL470104 0.93 NQO1 (0.64) NQO1TSHRTDP1APPLTA4H
SCHEMBL28147767 0.91 NQO1 (0.61) NQO1TSHRTDP1APPLTA4H
SCHEMBL28272644 0.89 NQO1 (0.58) NQO1TSHRTDP1APPKDM4E
SCHEMBL456905 0.89 NQO1 (0.58) NQO1TSHRTDP1APPLTA4H
1,4-Diethoxybenzene SCHEMBL28186701 0.86 NQO1 (1.00) NQO1TSHRTDP1LTA4HKDM4E
1,4-Diethoxybenzene SCHEMBL124015 0.86 NQO1 (1.00) NQO1TSHRTDP1LTA4HKDM4E
SCHEMBL1024643 0.83 APP (0.50) NQO1TSHRTDP1APPLTA4H
1,4-Diethoxybenzene SCHEMBL11794798 0.83 NQO1 (0.93) NQO1TSHRTDP1LTA4HKDM4E
Phenetole SCHEMBL27928366 0.81 LTA4H (0.57) NQO1TSHRTDP1APPLTA4H
1,4-Diethoxybenzene SCHEMBL27616183 0.80 NQO1 (0.88) NQO1TSHRTDP1LTA4HKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 256 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260140444-A1 PHOTORESIST COMPOSITION AND METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD. (TW) 2026-05-21 US claimed
US-10865163-B2 Carbon dioxide as a directing group for C—H functionalization reactions involving Lewis basic amines, alcohols, thiols, and phosphines for the synthesis of compounds THE UNIVERSITY OF TOLEDO (US) 2020-12-15 US claimed
US-20190185392-A1 Carbon Dioxide as a Directing Group for C-H Functionalization Reactions Involving Lewis Basic Amines, Alcohols, Thiols, and Phosphines for the Synthesis of Compounds THE UNIVERSITY OF TOLEDO (US) 2019-06-20 US claimed
US-20260140444-A1 PHOTORESIST COMPOSITION AND METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD. (TW) 2026-05-21 US disclosed
US-12566374-B2 Photoresist composition and method of manufacturing semiconductor device TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD. (TW) 2026-03-03 US disclosed
US-20250172873-A1 PHOTOSENSITIVE RESIN COMPOSITION, CURED ARTICLE, METHOD FOR MANUFACTURING CURED ARTICLE, ORGANIC EL DISPLAY DEVICE, AND DISPLAY DEVICE TORAY INDUSTRIES, INC. (JP) 2025-05-29 US disclosed
CN-119977743-A Method for rapidly preparing biphenyl compounds by catalyzing C-C coupling reaction through mechanical grinding method 辽宁大学 2025-05-13 CN disclosed
US-20250136555-A1 HYDANTOIN COMPOUND AND MEDICAL USE THEREOF HARBIN MEDISAN PHARMACEUTICAL CO., LTD. (CN) 2025-05-01 US disclosed
CN-119591596-A 4, 5-Dihydro-3H-pyrrolo [2,3-c ] quinolin-4-one derivatives and uses thereof 沈阳药科大学 2025-03-11 CN disclosed
CN-115354350-B Method for in-situ nitration of electrocatalytic halogenated aromatic hydrocarbon 平顶山学院 2025-02-25 CN disclosed
US-RE50267-E1 Modulators of the prostacyclin (PGI2) receptor useful for the treatment of disorders related thereto ARENA PHARMACEUTICALS, INC. (US) 2025-01-14 US disclosed
US-20020128270-A1 Piperazine compounds as inhibitors of MMP or TNF FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2002-09-12 US disclosed
US-6333324-B1 FOR THERAPY AND PROPHYLAXIS OF MATRIX METALLOPROTEINASES (MMP) OR TUMOR NECROSIS FACTOR .ALPHA. (TNF.ALPHA.), MEDIATED DISEASES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2001-12-25 US disclosed
US-6333080-B1 HIGH ANISOTROPY, HIGH ELASTIC CONSTANT RATIO, EXCELLENT COMPARABILITY WITH OTHER LIQUID-CRYSTAL COMPOUNDS, AND LOW VISCOSITY AND ARE CHEMICALLY AND PHYSICALLY STABLE CHISSO CORPORATION (JP) 2001-12-25 US disclosed
US-6201131-B1 REACTING A 2-(ARYLSUFONYL) ETHANOL DERIVATIVE WITH AN ACID ANHYDRIDE IN PRESENCE OF A BASE, FURTHER REACTING THIS WITH AN AROMATIC HALIDE IN THE PRESENCE OF A PALLADIUM CATALYST; USEFUL AS INTERMEDIATES TO DRUGS, AGROCHEMICALS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-03-13 US disclosed
EP-0948489-A1 PIPERAZINE COMPOUNDS AS INHIBITORS OF MMP OR TNF FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1999-10-13 EP disclosed
EP-0930286-A1 LIQUID-CRYSTAL ALKENYLTOLAN DERIVATIVE, LIQUID-CRYSTAL COMPOSITION, AND LIQUID-CRYSTAL DISPLAY ELEMENT CHISSO CORPORATION (JP) 1999-07-21 EP disclosed
WO-1998027069-A1 PIPERAZINE COMPOUNDS AS INHIBITORS OF MMP OR TNF FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1998-06-25 WO disclosed
US-5068053-A Liquid crystals for optical apparatus MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1991-11-26 US disclosed
US-4186153-A Process for 1,2,4,5-tetrachlorobenzene THE DOW CHEMICAL COMPANY (US) 1980-01-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260140444-A1 PHOTORESIST COMPOSITION AND METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE INO80C, INO80, NAT10 NQO1 4168/4885TSHR 242/4885TDP1 4386/4885
US-20190185392-A1 Carbon Dioxide as a Directing Group for C-H Functionalization Reactions Involving Lewis Basic Amines, Alcohols, Thiols, and Phosphines for the Synthesis of Compounds CHKB, HRH3, PNMT NQO1 1534/4885TSHR 1440/4885TDP1 4458/4885
US-12566374-B2 Photoresist composition and method of manufacturing semiconductor device INO80C, INO80, PI4K2B NQO1 4219/4885TSHR 191/4885TDP1 3931/4885
US-20020128270-A1 Piperazine compounds as inhibitors of MMP or TNF MMP1, MMP2, TNF NQO1 301/4885TSHR 1849/4885TDP1 2968/4885
US-10865163-B2 Carbon dioxide as a directing group for C—H functionalization reactions involving Lewis basic amines, alcohols, thiols, and phosphines for the synthesis of compounds CHKB, HRH3, PNMT NQO1 1502/4885TSHR 1464/4885TDP1 4491/4885
US-20250136555-A1 HYDANTOIN COMPOUND AND MEDICAL USE THEREOF PPARD, PPARA, PPARG NQO1 803/4885TSHR 1686/4885TDP1 3494/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.