Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 5/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL797517 | 0.83 | SLC6A4 (0.32) | SLC6A4DRD2GAA | |
| SCHEMBL5351880 | 0.81 | ALDH1A1 (0.35) | SLC6A4KDM4EALDH1A1LMNAMAPK1 | |
| SCHEMBL7599708 | 0.80 | KDM4E (0.31) | KDM4EALDH1A1LMNAMAPK1MAPT | |
| SCHEMBL7602562 | 0.80 | HTR1A (0.34) | HTR1AHTR7HTR2BTMEM97SIGMAR1 | |
| SCHEMBL7598778 | 0.77 | BRD4 (0.33) | HTR1AHTR7DRD2 | |
| SCHEMBL7599705 | 0.76 | KDM4E (0.32) | KDM4EALDH1A1LMNAMAPK1 | |
| SCHEMBL7597816 | 0.76 | KDM4E (0.32) | KDM4EALDH1A1LMNAMAPK1 | |
| SCHEMBL7599303 | 0.75 | HTR7 (0.36) | SLC6A4HTR1AHTR7DRD2KDM4E | |
| SCHEMBL7602945 | 0.73 | ADRA2C (0.31) | CYP1A2 | |
| SCHEMBL797107 | 0.73 | SLC6A4 (0.32) | SLC6A4HTR1AHTR7HTR2BTMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410665-B1 | POLYMERIZATION COORDINATION CATALYST FOR ALPHA-OLEFIN | BASELL POLYOLEFINE GMBH (DE) | 2002-06-25 | — | — | US | claimed |