Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | THRA | P10827 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7603075 | 0.91 | MAPT (0.46) | MAPTTHRBKMT2AMEN1NPSR1 | |
| SCHEMBL6738712 | 0.85 | MAPT (0.46) | MAPTTHRBKMT2AMEN1NPSR1 | |
| Metrafenone SCHEMBL29408434 | 0.84 | ALDH1A1 (0.42) | MAPTKMT2AMEN1NPSR1ALDH1A1 | |
| Metrafenone SCHEMBL30013482 | 0.84 | ALDH1A1 (0.42) | MAPTKMT2AMEN1NPSR1ALDH1A1 | |
| Metrafenone SCHEMBL20788 | 0.84 | ALDH1A1 (0.42) | MAPTKMT2AMEN1NPSR1ALDH1A1 | |
| SCHEMBL7602501 | 0.84 | THRA (0.46) | MAPTTHRATHRBKMT2AMEN1 | |
| SCHEMBL7601914 | 0.82 | MAPT (0.49) | MAPTKMT2AMEN1NPSR1ALDH1A1 | |
| SCHEMBL7044465 | 0.82 | PDE4A (0.47) | MAPTTHRATHRBKMT2AMEN1 | |
| Metrafenone SCHEMBL1613717 | 0.81 | HPGD (0.52) | MAPTALDH1A1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL7599649 | 0.80 | APP (0.41) | MAPTTHRBKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020155518-A1 | Method of detecting compounds that control fungal diseases via effects on sporulation | BASF AKTIENGESELLSCHAFT (DE) | 2002-10-24 | — | — | US | disclosed |