Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 7/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.32 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.32 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.32 |
| ▸ | ATP1B2 | P14415 | 1/20 | 0.32 |
| ▸ | ATP1A2 | P50993 | 1/20 | 0.32 |
| ▸ | ATP1B3 | P54709 | 1/20 | 0.32 |
| ▸ | FXYD2 | P54710 | 1/20 | 0.32 |
| ▸ | ATP1A4 | Q13733 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13646756 | 1.00 | CYP3A4 (0.36) | CYP3A4LMNASTAT3TP53SMN1; SMN2 | |
| SCHEMBL17145964 | 0.90 | CYP3A4 (0.39) | CYP3A4LMNASTAT3TP53SMN1; SMN2 | |
| SCHEMBL18390942 | 0.90 | CYP3A4 (0.35) | CYP3A4LMNASTAT3TP53SMN1; SMN2 | |
| SCHEMBL14819927 | 0.90 | CYP3A4 (0.39) | CYP3A4LMNASTAT3TP53SMN1; SMN2 | |
| SCHEMBL23277703 | 0.90 | CYP3A4 (0.39) | CYP3A4LMNASTAT3TP53SMN1; SMN2 | |
| SCHEMBL24106455 | 0.90 | CYP3A4 (0.39) | CYP3A4LMNASTAT3TP53SMN1; SMN2 | |
| SCHEMBL7602274 | 0.90 | CYP3A4 (0.35) | CYP3A4LMNASTAT3TP53SMN1; SMN2 | |
| SCHEMBL12848830 | 0.90 | CYP3A4 (0.39) | CYP3A4LMNASTAT3TP53SMN1; SMN2 | |
| SCHEMBL17676555 | 0.90 | CYP3A4 (0.35) | CYP3A4LMNASTAT3TP53SMN1; SMN2 | |
| SCHEMBL7155026 | 0.89 | LMNA (0.31) | CYP3A4LMNASTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1675474-B2 | PALATABLE DUCTILE CHEWABLE VETERINARY COMPOSITION | NOVARTIS TIERGESUNDHEIT AG (CH) | 2016-12-07 | — | — | EP | disclosed |
| EP-2219643-B1 | ANTHELMINTIC PASTE COMPRISING PRAZIQUANTEL, A MACROLIDE LACTONE, CYCLODEXTRIN AND A THICKENER | NOVARTIS AG (CH) | 2012-05-16 | — | — | EP | disclosed |
| US-7964635-B2 | Amidoacetonitrile derivatives | NOVARTIS AG (CH) | 2011-06-21 | — | — | US | disclosed |
| US-7964635-B2 | Amidoacetonitrile derivatives | NOVARTIS AG (CH) | 2011-06-21 | — | — | US | disclosed |
| US-20100286154-A1 | ANTIHELMINTIC PASTE | NOVARTIS TIERGESUNDHEIT AG (CH) | 2010-11-11 | — | — | US | disclosed |
| US-20100286154-A1 | ANTIHELMINTIC PASTE | NOVARTIS TIERGESUNDHEIT AG (CH) | 2010-11-11 | — | — | US | disclosed |
| US-7705047-B2 | Amidoacetonitrile derivatives | NOVARTIS AG (CH) | 2010-04-27 | — | — | US | disclosed |
| US-7705047-B2 | Amidoacetonitrile derivatives | NOVARTIS AG (CH) | 2010-04-27 | — | — | US | disclosed |
| US-7642379-B2 | Aminoacetonitrile derivatives and their use for controlling parasites on warm-blooded animals | NOVARTIS AG (CH) | 2010-01-05 | — | — | US | disclosed |
| US-7642379-B2 | Aminoacetonitrile derivatives and their use for controlling parasites on warm-blooded animals | NOVARTIS AG (CH) | 2010-01-05 | — | — | US | disclosed |
| US-7494956-B2 | N-[1-cyano-1-methyl-2-(4-cyano-2-chlorophenoxy)-ethyl]-4-trifluoromethylbenzamide; etherification with a cyano-halobenzene in the presence of a basic catalyst; parasiticides, especially antihelmintics; veterinary medicine | NOVARTIS AG (CH) | 2009-02-24 | — | — | US | disclosed |
| US-7494956-B2 | N-[1-cyano-1-methyl-2-(4-cyano-2-chlorophenoxy)-ethyl]-4-trifluoromethylbenzamide; etherification with a cyano-halobenzene in the presence of a basic catalyst; parasiticides, especially antihelmintics; veterinary medicine | NOVARTIS AG (CH) | 2009-02-24 | — | — | US | disclosed |
| EP-1682493-B1 | AMIDOACETONITRILE DERIVATIVES | NOVARTIS AG (CH) | 2009-01-07 | — | — | EP | disclosed |
| EP-1675474-B1 | PALATABLE DUCTILE CHEWABLE VETERINARY COMPOSITION | NOVARTIS AG (CH) | 2008-10-22 | — | — | EP | disclosed |
| US-20080194693-A1 | Aminoacetonitrile Derivatives and Their Use for Controlling Parasites on Warm-Blooded Animals | NOVARTIS AG (CH) | 2008-08-14 | — | — | US | disclosed |
| US-20080194693-A1 | Aminoacetonitrile Derivatives and Their Use for Controlling Parasites on Warm-Blooded Animals | NOVARTIS AG (CH) | 2008-08-14 | — | — | US | disclosed |
| US-20070072944-A1 | Amidoacetonitrile derivatives | ELANCO TIERGESUNDHEIT AG (CH) | 2007-03-29 | — | — | US | disclosed |
| US-20070072944-A1 | Amidoacetonitrile derivatives | ELANCO TIERGESUNDHEIT AG (CH) | 2007-03-29 | — | — | US | disclosed |
| US-20070037881-A1 | N-[1-cyano-1-methyl-2-(5-cyano-2-{2,4-dichlorophenoxy}-phenoxy)-ethyl]-4-trifluoromethoxybenzamide; etherification with a cyano-halobenzene in the presence of a basic catalyst; parasiticides, especially antihelmintics; veterinary medicine | ELANCO TIERGESUNDHEIT AG (CH) | 2007-02-15 | — | — | US | disclosed |
| US-20070037881-A1 | N-[1-cyano-1-methyl-2-(5-cyano-2-{2,4-dichlorophenoxy}-phenoxy)-ethyl]-4-trifluoromethoxybenzamide; etherification with a cyano-halobenzene in the presence of a basic catalyst; parasiticides, especially antihelmintics; veterinary medicine | ELANCO TIERGESUNDHEIT AG (CH) | 2007-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194693-A1 | Aminoacetonitrile Derivatives and Their Use for Controlling Parasites on Warm-Blooded Animals | MB, ACHE, ADORA2B | CYP3A4 554/4885LMNA 1834/4885STAT3 4064/4885 |
| US-20070072944-A1 | Amidoacetonitrile derivatives | ACHE, NGLY1, NIT2 | CYP3A4 1660/4885LMNA 195/4885STAT3 4268/4885 |
| US-20100286154-A1 | ANTIHELMINTIC PASTE | PIGS, CTRL, SI | CYP3A4 637/4885LMNA 1367/4885STAT3 4212/4885 |
| US-20070037881-A1 | N-[1-cyano-1-methyl-2-(5-cyano-2-{2,4-dichlorophenoxy}-phenoxy)-ethyl]-4-trifluoromethoxybenzamide; etherification with a cyano-halobenzene in the presence of a basic catalyst; parasiticides, especially antihelmintics; veterinary medicine | CMA1, H1-2, H1-0 | CYP3A4 728/4885LMNA 531/4885STAT3 3402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.