⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9447194 | 0.75 | — | — | |
| SCHEMBL25426418 | 0.72 | ALDH1A1 (0.44) | — | |
| SCHEMBL9567513 | 0.69 | AHR (0.50) | — | |
| SCHEMBL8372529 | 0.65 | NPC1 (0.37) | — | |
| SCHEMBL63468 | 0.64 | ALDH1A1 (0.67) | — | |
| SCHEMBL32689722 | 0.62 | KMT2A (0.44) | — | |
| SCHEMBL609810 | 0.62 | DGAT1 (0.45) | — | |
| SCHEMBL7603891 | 0.62 | KDM4E (0.43) | — | |
| SCHEMBL31541140 | 0.62 | — | — | |
| SCHEMBL1931574 | 0.60 | HSD17B10 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104478911-A | Method for preparing 3-trifluoromethyl pyrrole boric acid | CHENGDU ASLEE BIOPHARMACEUTICALS INC | 2015-04-01 | — | — | CN | claimed |
| JP-1083063-A | — | — | None | — | — | JP | disclosed |
| JP-4360868-A | — | — | None | — | — | JP | disclosed |
| CN-119661621-A | Steroid compound, preparation method thereof, pharmaceutical composition and application | 北京华睿鼎信科技有限公司 | 2025-03-21 | — | — | CN | disclosed |
| CN-115925698-B | Imidazo [4,5-g ] quinolin-2-one compounds and their use as pesticides | 中新科农(山东)生态农业有限公司 | 2025-02-25 | — | — | CN | disclosed |
| WO-2023131122-A1 | FUSED RING-SUBSTITUTED SIX-MEMBERED HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 劲方医药科技(上海)有限公司 | 2023-07-13 | — | — | WO | disclosed |
| US-11667634-B2 | Inhibitors of RAF kinases | KINNATE BIOPHARMA INC. (US) | 2023-06-06 | — | — | US | disclosed |
| US-11667634-B2 | Inhibitors of RAF kinases | KINNATE BIOPHARMA INC. (US) | 2023-06-06 | — | — | US | disclosed |
| US-20220298142-A1 | HETEROCYCLIC COMPOUNDS AS ADENOSINE ANTAGONISTS | SAGARD HOLDINGS MANAGER LP, AS ADMINISTRATIVE AGENT (CA) | 2022-09-22 | — | — | US | disclosed |
| CN-114746090-A | Azaindole carboxamide compounds for the treatment of mycobacterial infections | 结核病药物开发全球联盟公司 | 2022-07-12 | — | — | CN | disclosed |
| US-20100273648-A1 | Synergistic Fungicidal Active Substance Combinations | BAYER CROPSCIENCE AG (DE) | 2010-10-28 | — | — | US | disclosed |
| WO-2010005528-A2 | PYRROLOPYRIDINE CARBOXYLIC ACID DERIVATIVES | IRONWOOD PHARMACEUTICALS INCORPORATED (US) | 2010-01-14 | — | — | WO | disclosed |
| EP-2142516-A1 | PYRIMIDINE HYDRAZIDE COMPOUNDS AS PGDS INHIBITORS | Sanofi-Aventis (FR) | 2010-01-13 | — | — | EP | disclosed |
| US-7612218-B2 | Process for production of heteroaryl-type boron compounds with iridium catalyst | MITSUBISHI RAYON CO., LTD. (JP) | 2009-11-03 | — | — | US | disclosed |
| WO-2008121670-A1 | PYRIMIDINE HYDRAZIDE COMPOUNDS AS PGDS INHIBITORS | SANOFI-AVENTIS (FR) | 2008-10-09 | — | — | WO | disclosed |
| US-20050148775-A1 | Process for production of heteroaryl-type boron compounds with iridium catalyst | MITSUBISHI RAYON CO., LTD. (JP) | 2005-07-07 | — | — | US | disclosed |
| EP-1481978-A1 | PROCESS FOR PRODUCTION OF HETEROARYL-TYPE BORON COMPOUNDS WITH IRIDIUM CATALYST | Mitsubishi Rayon Co., Ltd. (JP) | 2004-12-01 | — | — | EP | disclosed |
| CN-1026206-C | Arylpyrrole insecticidal acaricidal and nematicidal agents and method for preparation thereof | AMERICAN CYANAMID CO (US) | 1994-10-19 | — | — | CN | disclosed |
| JP-H04360868-A | TRIFLUROMETHYLPYRROLE DERIVATIVE AND PREVENTIVE AND THERAPEUTIC MEDICINE FOR LIVER DISEASE CONTAINING THE SAME DERIVATIVE | CENTRAL GLASS CO LTD | 1992-12-14 | — | — | JP | disclosed |
| CN-1039807-A | Desinsection, kill mite, nematocides aryl-pyrrolidine and preparation method thereof | AMERICAN CYANAMID CO (US) | 1990-02-21 | — | — | CN | disclosed |