Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MMP1 | P03956 | 3/20 | 0.43 |
| ▸ | MMP9 | P14780 | 3/20 | 0.43 |
| ▸ | MMP13 | P45452 | 3/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | MMP8 | P22894 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7597216 | 0.88 | KMT2A (0.44) | SMN1; SMN2NPC1KMT2ARAB9AMMP1 | |
| SCHEMBL59130 | 0.86 | ALDH1A1 (0.47) | SMN1; SMN2KMT2ARAB9AMAPTPOLB | |
| SCHEMBL952171 | 0.85 | KMT2A (0.49) | SMN1; SMN2NPC1KMT2ARAB9ALMNA | |
| SCHEMBL5527025 | 0.85 | MMP1 (0.53) | SMN1; SMN2NPC1KMT2ARAB9AMMP1 | |
| SCHEMBL7602645 | 0.84 | PRMT5 (0.43) | KMT2AMMP1MMP9MMP13MMP2 | |
| SCHEMBL8818910 | 0.80 | ALDH1A1 (0.45) | SMN1; SMN2NPC1KMT2ARAB9ACA2 | |
| SCHEMBL3253710 | 0.80 | PTGS2 (0.42) | SMN1; SMN2NPC1KMT2ARAB9ACYP19A1 | |
| SCHEMBL9550116 | 0.80 | ALDH1A1 (0.44) | SMN1; SMN2KMT2ARAB9AMAPTPOLB | |
| SCHEMBL2574007 | 0.78 | NPC1 (0.40) | SMN1; SMN2NPC1KMT2ARAB9ACA2 | |
| SCHEMBL9550112 | 0.77 | ALDH1A1 (0.43) | SMN1; SMN2KMT2ARAB9AMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492075-B1 | COATING WITH CLEAVING COMPOUND TO CONTROLLABLY DECREASE SIZE OF DEVELOPED RESIST | ADVANCED MICRO DEVICES, INC. | 2002-12-10 | — | — | US | disclosed |
| US-6274289-B1 | Chemical resist thickness reduction process | ADVANCED MICRO DEVICES, INC. | 2001-08-14 | — | — | US | disclosed |
| EP-0848288-A1 | Resist materials | LUCENT TECHNOLOGIES INC. (US) | 1998-06-17 | — | — | EP | disclosed |
| US-4996136-A | Radiation sensitive materials and devices made therewith | AT&T BELL LABORATORIES (US) | 1991-02-26 | — | — | US | disclosed |