Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 7/20 | 0.35 |
| ▸ | CDK2AP1 | O14519 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7558108 | 0.72 | SLC6A4 (0.37) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4475880 | 0.68 | HSD11B1 (0.41) | HSD11B1CHEK1KCNH2 | |
| SCHEMBL3432643 | 0.65 | OPRD1 (0.45) | CHEK1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6508980 | 0.65 | KMT2A (0.48) | CHEK1CDK2AP1SLC6A4SLC6A3 | |
| SCHEMBL3299919 | 0.64 | SLC6A4 (0.39) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3297642 | 0.64 | SLC6A4 (0.39) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3297878 | 0.64 | SLC6A4 (0.39) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3297637 | 0.64 | SLC6A4 (0.39) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4671412 | 0.63 | MGLL (0.49) | — | |
| SCHEMBL7354541 | 0.63 | OPRM1 (0.41) | CHEK1SLC6A4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002069895-A2 | HETEROCYCLIC ANALGESIC COMPOUNDS AND METHODS OF USE THEREOF | SEPRACOR, INC. (US) | 2002-09-12 | — | — | WO | disclosed |