Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 4/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 12/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | F7 | P08709 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.36 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7605292 | 0.88 | ACP1 (0.42) | NR3C1ADRB3CYP19A1ALDH1A1 | |
| SCHEMBL7611069 | 0.83 | MEN1 (0.37) | F2F10PRSS1F7MEN1 | |
| SCHEMBL7609423 | 0.83 | ADRB3 (0.40) | NR3C1ADRB3CYP19A1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7608285 | 0.83 | ADRB3 (0.40) | NR3C1ADRB3CYP19A1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7610067 | 0.82 | AR (0.38) | NR3C1ADRB3CYP19A1MEN1ALDH1A1 | |
| SCHEMBL7606900 | 0.82 | ADRB3 (0.38) | NR3C1ADRB3CYP19A1SMN1; SMN2PGR | |
| SCHEMBL7606895 | 0.81 | ABCB1 (0.44) | MEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL7610741 | 0.80 | ADRB3 (0.33) | ADRB3ADRB2ADRB1 | |
| SCHEMBL7614703 | 0.79 | SMN1; SMN2 (0.41) | NR3C1CYP19A1MEN1ALDH1A1KMT2A | |
| SCHEMBL7611191 | 0.77 | ALDH1A1 (0.44) | MEN1ALDH1A1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1230210-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001036375-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-25 | — | — | WO | disclosed |