Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | CTSV | O60911 | 4/20 | 0.42 |
| ▸ | CTSL | P07711 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 4/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7606585 | 0.88 | CTSV (0.44) | ABCB1CTSVCTSLMEN1KMT2A | |
| SCHEMBL7607653 | 0.88 | CTSV (0.44) | ABCB1CTSVCTSLMEN1KMT2A | |
| SCHEMBL7608191 | 0.87 | FFAR1 (0.43) | ABCB1CTSVCTSLMAPTPDCD1 | |
| SCHEMBL7604662 | 0.87 | MEN1 (0.44) | ABCB1CTSVCTSLMEN1KMT2A | |
| SCHEMBL7605326 | 0.86 | CTSV (0.42) | ABCB1CTSVCTSLMEN1KMT2A | |
| SCHEMBL4728111 | 0.85 | KMT2A (0.43) | ABCB1CTSVCTSLMEN1KMT2A | |
| SCHEMBL7611069 | 0.85 | MEN1 (0.37) | MEN1KMT2APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL7608529 | 0.82 | FFAR1 (0.40) | ABCB1CTSVCTSLMEN1KMT2A | |
| SCHEMBL7609875 | 0.82 | PRKCA (0.41) | ABCB1CTSVCTSLMEN1KMT2A | |
| SCHEMBL7604970 | 0.81 | NR3C1 (0.43) | MEN1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1230210-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001036375-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-25 | — | — | WO | disclosed |