Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | EGFR | P00533 | 3/20 | 0.54 |
| ▸ | SRC | P12931 | 1/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL311067 | 0.98 | KEAP1 (0.60) | KEAP1KDM4EALDH1A1EGFRSRC | |
| SCHEMBL29564062 | 0.98 | KEAP1 (0.60) | KEAP1KDM4EALDH1A1EGFRSRC | |
| SCHEMBL7605316 | 0.95 | KEAP1 (0.58) | KEAP1KDM4EALDH1A1EGFRSRC | |
| Phenyl Propionic Acid SCHEMBL7826574 | 0.90 | KEAP1 (0.76) | KEAP1KDM4EALDH1A1FFAR1HDAC3 | |
| SCHEMBL9782880 | 0.88 | FFAR1 (0.68) | KEAP1KDM4EALDH1A1EGFRSRC | |
| SCHEMBL11987690 | 0.88 | EGFR (0.50) | KEAP1KDM4EALDH1A1EGFRSRC | |
| SCHEMBL9426100 | 0.88 | ALDH1A1 (0.50) | KEAP1KDM4EALDH1A1EGFRSRC | |
| SCHEMBL9782874 | 0.86 | KEAP1 (0.59) | KEAP1KDM4EALDH1A1EGFRSRC | |
| SCHEMBL9782888 | 0.85 | RXFP1 (0.53) | KEAP1KDM4EALDH1A1EGFRSRC | |
| SCHEMBL28613421 | 0.84 | HDAC3 (0.63) | KEAP1KDM4EALDH1A1EGFRFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107429075-B | Activatable two-component photosensitizer | 卡内基梅隆大学 | 2022-11-01 | — | — | CN | disclosed |
| CN-113713096-B | Naphthalocyanine copper and Au composite material and preparation method and application thereof | 河南大学 | 2022-06-24 | — | — | CN | disclosed |
| CN-113713096-A | Naphthalocyanine copper self-assembly material, naphthalocyanine copper and Au composite material, and preparation method and application thereof | 河南大学 | 2021-11-30 | — | — | CN | disclosed |
| US-10946098-B2 | Activatable two-component photosensitizers | CARNEGIE MELLON UNIVERSITY (US) | 2021-03-16 | — | — | US | disclosed |
| US-20200078460-A1 | Activatable Two-Component Photosensitizers | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2020-03-12 | — | — | US | disclosed |
| US-10434177-B2 | Activatable two-component photosensitizers | CARNEGIE MELLON UNIVERSITY (US) | 2019-10-08 | — | — | US | disclosed |
| US-20180280510-A1 | Activatable Two-Component Photosensitizers | CARNEGIE MELLON UNIVERSITY | 2018-10-04 | — | — | US | disclosed |
| WO-2016081440-A1 | ACTIVATABLE TWO-COMPONENT PHOTOSENSITIZERS | CARNEGIE MELLON UNIVERSITY (US) | 2016-05-26 | — | — | WO | disclosed |
| US-20020164651-A1 | Diagnostic for inflammatory diseases associated with cartilage and bone surfaces | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2002-11-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200078460-A1 | Activatable Two-Component Photosensitizers | FAP, APC, FOSB | KEAP1 4415/4885KDM4E 3371/4885ALDH1A1 2313/4885 |
| US-10946098-B2 | Activatable two-component photosensitizers | FAP, APC, FOSB | KEAP1 4415/4885KDM4E 3371/4885ALDH1A1 2313/4885 |
| US-10434177-B2 | Activatable two-component photosensitizers | FAP, APC, FOSB | KEAP1 4415/4885KDM4E 3371/4885ALDH1A1 2313/4885 |
| US-20180280510-A1 | Activatable Two-Component Photosensitizers | FAP, APC, FOSB | KEAP1 4415/4885KDM4E 3371/4885ALDH1A1 2313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.