Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.85 |
| ▸ | NPC1 | O15118 | 7/20 | 0.85 |
| ▸ | MAPT | P10636 | 3/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.70 |
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | USP2 | O75604 | 1/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | SNCA | P37840 | 1/20 | 0.64 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.64 |
| ▸ | NQO2 | P16083 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | NAMPT | P43490 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | AURKA | O14965 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6555948 | 1.00 | RAB9A (0.85) | RAB9ANPC1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL20284419 | 0.95 | NPC1 (0.76) | RAB9ANPC1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL27181403 | 0.92 | RAB9A (1.00) | RAB9ANPC1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL14580374 | 0.92 | RAB9A (1.00) | RAB9ANPC1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL12310125 | 0.92 | RAB9A (1.00) | RAB9ANPC1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL15214321 | 0.92 | RAB9A (1.00) | RAB9ANPC1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL822378 | 0.92 | RAB9A (1.00) | RAB9ANPC1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL899585 | 0.90 | DEGS1 (0.75) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL900928 | 0.90 | DEGS1 (0.75) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8420639 | 0.90 | DEGS1 (0.75) | RAB9ANPC1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1102743-B1 | AMIDE DERIVATIVES WHICH ARE USEFUL AS CYTOKINE INHIBITORS | ASTRAZENECA AB (SE) | 2002-07-24 | — | — | EP | claimed |
| EP-0409313-A2 | Poly carbonates endowed with high-fluidity characteristics and process for preparing them | ENICHEM S.p.A. (IT) | 1991-01-23 | — | — | EP | claimed |
| CN-1243724-C | Amide derivatives which are useful as cell factor inhibitors | ASTRA ZENECA LTD (SE) | 2006-03-01 | — | — | CN | disclosed |
| EP-1102743-B1 | AMIDE DERIVATIVES WHICH ARE USEFUL AS CYTOKINE INHIBITORS | ASTRAZENECA AB (SE) | 2002-07-24 | — | — | EP | disclosed |
| EP-0409313-A2 | Poly carbonates endowed with high-fluidity characteristics and process for preparing them | ENICHEM S.p.A. (IT) | 1991-01-23 | — | — | EP | disclosed |