Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | UBE2M | P61081 | 2/20 | 0.30 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5057852 | 0.74 | FOLH1 (0.48) | — | |
| SCHEMBL8064187 | 0.74 | PTPN1 (0.38) | ALDH1A1 | |
| SCHEMBL3219002 | 0.72 | PGK1 (0.48) | — | |
| SCHEMBL28909637 | 0.65 | CES2 (0.36) | — | |
| SCHEMBL5051331 | 0.63 | GGH (0.51) | — | |
| SCHEMBL5052921 | 0.63 | FOLH1 (0.34) | ALDH1A1HPGD | |
| SCHEMBL28909686 | 0.63 | CES2 (0.35) | — | |
| SCHEMBL779939 | 0.63 | TAS1R3 (0.35) | ALDH1A1 | |
| SCHEMBL878885 | 0.62 | FDPS (0.54) | — | |
| SCHEMBL206670 | 0.60 | CES2 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002514184-A | — | — | 2002-05-14 | — | — | JP | claimed |
| EP-1005348-A1 | NAALADASE COMPOSITIONS AND METHODS FOR TREATING GLUTAMATE ABNORMALITY AND EFFECTING NEURONAL ACTIVITY IN ANIMALS | GUILFORD PHARMACEUTICALS INC. (US) | 2000-06-07 | — | — | EP | claimed |
| WO-1998013046-A1 | NAALADASE COMPOSITIONS AND METHODS FOR TREATING GLUTAMATE ABNORMALITY AND EFFECTING NEURONAL ACTIVITY IN ANIMALS | GUILFORD PHARMACEUTICALS INC. (US) | 1998-04-02 | — | — | WO | claimed |