Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 12/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CASR | P41180 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11251333 | 0.81 | NPC1 (0.48) | ADRB3LMNAKMT2AADRB2ADRB1 | |
| SCHEMBL7609934 | 0.79 | ADRB3 (0.43) | ADRB3LMNAKMT2AADRB2ADRB1 | |
| Sulfuric Acid SCHEMBL7540439 | 0.77 | SMN1; SMN2 (0.44) | LMNAKMT2AMEN1GAAALDH1A1 | |
| SCHEMBL7536032 | 0.76 | KMT2A (0.43) | ADRB3LMNAKMT2AADRB2ADRB1 | |
| SCHEMBL7608796 | 0.76 | ADRB3 (0.60) | ADRB3ADRB2ADRB1 | |
| SCHEMBL7768377 | 0.76 | SMN1; SMN2 (0.48) | LMNAKMT2AMEN1GAAALDH1A1 | |
| SCHEMBL7609836 | 0.76 | ADRB3 (0.47) | ADRB3LMNAKMT2AADRB2ADRB1 | |
| SCHEMBL7607621 | 0.75 | ADRB2 (0.68) | ADRB3KMT2AADRB2ADRB1MEN1 | |
| Hydrochloric Acid SCHEMBL7764617 | 0.75 | KMT2A (0.46) | LMNAKMT2AMEN1MAPK1ALDH1A1 | |
| SCHEMBL7605257 | 0.74 | KMT2A (0.41) | LMNAKMT2AADRB2ADRB1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1230210-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001036375-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-25 | — | — | WO | disclosed |