Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 5/20 | 0.34 |
| ▸ | SLC29A1 | Q99808 | 5/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31286711 | 0.86 | SCN9A (0.44) | SCN9AHRH1DRD2SLC29A1SIGMAR1 | |
| SCHEMBL7612299 | 0.85 | TACR1 (0.35) | SCN9ADRD2SIGMAR1TLR8 | |
| SCHEMBL7604209 | 0.82 | USP2 (0.43) | SMN1; SMN2EPHX2CHRM3TLR8 | |
| SCHEMBL7640664 | 0.79 | CTSK (0.34) | MEN1KMT2A | |
| SCHEMBL31286699 | 0.77 | SCN9A (0.41) | SCN9AHRH1DRD2SIGMAR1SMN1; SMN2 | |
| SCHEMBL249745 | 0.75 | DRD2 (0.36) | DRD2SIGMAR1 | |
| SCHEMBL31286870 | 0.75 | SCN9A (0.44) | SCN9AHRH1SIGMAR1MEN1HTR2A | |
| SCHEMBL20305593 | 0.74 | SCN9A (0.43) | SCN9AHRH1DRD2SLC29A1SIGMAR1 | |
| SCHEMBL20372563 | 0.73 | SCN9A (0.39) | SCN9AHRH1DRD2SLC29A1SIGMAR1 | |
| SCHEMBL7611072 | 0.73 | HRH1 (0.41) | HRH1DRD2SLC29A1SMN1; SMN2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927173-B1 | SUBSTITUTED [2-(1-PIPERAZINYL)ETHOXY]METHYL | UCB SA (BE) | 2002-06-12 | — | — | EP | claimed |