Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 14/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 12/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 7/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7028696 | 0.79 | ADRB1 (0.50) | ADRB1ADRB3ADRB2MEN1KMT2A | |
| SCHEMBL7032501 | 0.76 | ALDH1A1 (0.51) | ADRB1ADRB3ALDH1A1 | |
| SCHEMBL7768357 | 0.76 | ADRB1 (0.44) | ADRB1ADRB3ADRB2MEN1KMT2A | |
| SCHEMBL7597017 | 0.75 | MEN1 (0.53) | ADRB1ADRB3ADRB2MEN1KMT2A | |
| SCHEMBL7024944 | 0.75 | ADRB1 (0.50) | ADRB1ADRB3ADRB2MEN1KMT2A | |
| SCHEMBL7536025 | 0.71 | NPC1 (0.51) | ADRB1ADRB3ADRB2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7605228 | 0.70 | CYP2D6 (0.55) | ADRB1ADRB3ADRB2MEN1KMT2A | |
| SCHEMBL7027312 | 0.69 | MEN1 (0.65) | ADRB1ADRB3ADRB2MEN1KMT2A | |
| SCHEMBL7608535 | 0.68 | TSHR (0.41) | MEN1KMT2AALDH1A1 | |
| SCHEMBL7032860 | 0.68 | SMN1; SMN2 (0.43) | MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1230210-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001036375-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-25 | — | — | WO | disclosed |