Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | UBE2M | P61081 | 6/20 | 0.37 |
| ▸ | DCUN1D1 | Q96GG9 | 6/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7610293 | 0.77 | RAB9A (0.46) | MEN1KMT2ANR3C1ALDH1A1RAB9A | |
| SCHEMBL7768607 | 0.75 | SMN1; SMN2 (0.44) | MEN1KMT2ANR3C1ALDH1A1RAB9A | |
| SCHEMBL7032860 | 0.74 | SMN1; SMN2 (0.43) | MEN1KMT2AUSP2UBE2MDCUN1D1 | |
| SCHEMBL7032501 | 0.72 | ALDH1A1 (0.51) | TSHRALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL6027885 | 0.72 | SMN1; SMN2 (0.46) | TSHRMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL6319157 | 0.69 | SMN1; SMN2 (0.48) | MEN1KMT2ANR3C1ALDH1A1RAB9A | |
| SCHEMBL6319153 | 0.69 | SMN1; SMN2 (0.48) | MEN1KMT2ANR3C1ALDH1A1RAB9A | |
| SCHEMBL7593750 | 0.69 | SMN1; SMN2 (0.49) | MEN1KMT2AALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL7028479 | 0.69 | RXFP1 (0.42) | MEN1KMT2AATMUSP2RAB9A | |
| SCHEMBL7608531 | 0.68 | ADRB1 (0.42) | MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1230210-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001036375-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-25 | — | — | WO | disclosed |