Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.49 |
| ▸ | HTR6 | P50406 | 9/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR7 | P34969 | 2/20 | 0.41 |
| ▸ | ELAVL1 | Q15717 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 2/20 | 0.38 |
| ▸ | PTPRC | P08575 | 1/20 | 0.38 |
| ▸ | PTPRF | P10586 | 1/20 | 0.38 |
| ▸ | PPME1 | Q9Y570 | 1/20 | 0.38 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7599738 | 0.74 | BACE1 (0.51) | BACE1PTPN1MEN1ALDH1A1LMNA | |
| SCHEMBL7602586 | 0.71 | BACE1 (0.49) | BACE1PTPN1ALDH1A1HPGDCDC25B | |
| SCHEMBL6555840 | 0.70 | BACE1 (0.75) | BACE1PTPN1MEN1ALDH1A1LMNA | |
| SCHEMBL7598965 | 0.69 | BACE1 (0.48) | BACE1PTPN1MEN1ALDH1A1LMNA | |
| SCHEMBL7600067 | 0.68 | BACE1 (0.56) | BACE1PTPN1MEN1ALDH1A1LMNA | |
| SCHEMBL29673492 | 0.67 | BACE1 (1.00) | BACE1PTPN1MEN1ALDH1A1LMNA | |
| SCHEMBL5485068 | 0.67 | BACE1 (1.00) | BACE1PTPN1MEN1ALDH1A1LMNA | |
| SCHEMBL29582923 | 0.67 | HTR6 (0.43) | HTR6HTR1ADRD2HTR2AHTR7 | |
| SCHEMBL26909744 | 0.67 | HTR6 (0.43) | HTR6HTR1ADRD2HTR2AHTR7 | |
| SCHEMBL7600422 | 0.66 | BACE1 (0.44) | BACE1PTPN1MEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861830-B1 | Use of 1,4-naphthoquinone and 1,4-dihydroxynaphthalene pyrrole derivatives for dyeing keratinous material, compounds and compositions containing them | OREAL (FR) | 2002-12-18 | — | — | EP | claimed |
| US-6022379-A | HAIR DYE | L'OREAL (FR) | 2000-02-08 | — | — | US | claimed |
| US-6022379-A | HAIR DYE | L'OREAL (FR) | 2000-02-08 | — | — | US | disclosed |