Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7768607 | 0.90 | SMN1; SMN2 (0.44) | RAB9ASMN1; SMN2NPC1NR3C1HPGD | |
| SCHEMBL7612363 | 0.86 | NPC1 (0.48) | RAB9ASMN1; SMN2NPC1NR3C1LMNA | |
| SCHEMBL7611594 | 0.82 | MAPT (0.48) | RAB9ASMN1; SMN2NPC1NR3C1HPGD | |
| SCHEMBL7609951 | 0.81 | SMN1; SMN2 (0.36) | RAB9ASMN1; SMN2NPC1NR3C1LMNA | |
| SCHEMBL7605880 | 0.81 | NPC1 (0.43) | RAB9ASMN1; SMN2NPC1NR3C1LMNA | |
| SCHEMBL7607642 | 0.77 | NPC1 (0.47) | RAB9ASMN1; SMN2NPC1NR3C1HPGD | |
| SCHEMBL7608535 | 0.77 | TSHR (0.41) | RAB9ASMN1; SMN2NPC1NR3C1LMNA | |
| SCHEMBL6027885 | 0.76 | SMN1; SMN2 (0.46) | RAB9ASMN1; SMN2NPC1LMNAALDH1A1 | |
| SCHEMBL7769464 | 0.75 | CASR (0.46) | RAB9ASMN1; SMN2NPC1HPGDLMNA | |
| SCHEMBL7610290 | 0.75 | POLB (0.57) | RAB9ASMN1; SMN2NPC1NR3C1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1230210-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001036375-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-25 | — | — | WO | disclosed |