Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CASR | P41180 | 2/20 | 0.41 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.37 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7610293 | 0.90 | RAB9A (0.46) | SMN1; SMN2RAB9ANPC1NR3C1HPGD | |
| SCHEMBL7607642 | 0.86 | NPC1 (0.47) | SMN1; SMN2RAB9ANPC1NR3C1HPGD | |
| SCHEMBL7769464 | 0.86 | CASR (0.46) | SMN1; SMN2RAB9ANPC1HPGDLMNA | |
| SCHEMBL7764640 | 0.84 | LPAR1 (0.41) | SMN1; SMN2RAB9ANPC1HPGDLMNA | |
| SCHEMBL7764648 | 0.84 | KMT2A (0.47) | SMN1; SMN2RAB9ANPC1HPGDLMNA | |
| SCHEMBL7610980 | 0.83 | MEN1 (0.44) | SMN1; SMN2RAB9ANPC1HPGDLMNA | |
| SCHEMBL7611484 | 0.82 | ALDH1A1 (0.38) | SMN1; SMN2RAB9ANPC1HPGDLMNA | |
| SCHEMBL7024089 | 0.79 | SMN1; SMN2 (0.51) | SMN1; SMN2RAB9ANPC1NR3C1HPGD | |
| SCHEMBL7612363 | 0.77 | NPC1 (0.48) | SMN1; SMN2RAB9ANPC1NR3C1LMNA | |
| SCHEMBL7688371 | 0.75 | POLB (0.54) | SMN1; SMN2RAB9ANPC1NR3C1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1107944-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA 3 ADRENERGIC AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000012462-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA 3 ADRENERGIC AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-03-09 | — | — | WO | disclosed |