Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7764640 | 0.90 | LPAR1 (0.41) | ALDH1A1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL7764648 | 0.86 | KMT2A (0.47) | ALDH1A1TSHRMAPTRAB9AMEN1 | |
| SCHEMBL7768607 | 0.86 | SMN1; SMN2 (0.44) | CASRALDH1A1MAPTRAB9AMEN1 | |
| SCHEMBL7610980 | 0.85 | MEN1 (0.44) | ALDH1A1CYP3A4TSHRMAPTRAB9A | |
| SCHEMBL7611484 | 0.84 | ALDH1A1 (0.38) | ALDH1A1CYP3A4TSHRMAPTRAB9A | |
| SCHEMBL6027885 | 0.76 | SMN1; SMN2 (0.46) | ALDH1A1CYP3A4TSHRRAB9AMEN1 | |
| SCHEMBL7610293 | 0.75 | RAB9A (0.46) | ALDH1A1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL6322105 | 0.74 | ALDH1A1 (0.58) | CASRALDH1A1TSHRMAPTRAB9A | |
| SCHEMBL7612302 | 0.73 | ALOX5 (0.45) | ALDH1A1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL7607642 | 0.73 | NPC1 (0.47) | CASRALDH1A1TSHRMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1107944-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA 3 ADRENERGIC AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000012462-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA 3 ADRENERGIC AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-03-09 | — | — | WO | disclosed |