Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.59 |
| ▸ | MAOB | P27338 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | DRD4 | P21917 | 2/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10511421 | 0.89 | ACHE (0.60) | ACHEMAOBGAADRD2DRD4 | |
| SCHEMBL21966595 | 0.89 | ACHE (0.52) | ACHEMAOBGAADRD2DRD4 | |
| Hydrochloric Acid SCHEMBL10555496 | 0.87 | ACHE (0.58) | ACHEMAOBGAADRD2DRD4 | |
| Hydrochloric Acid SCHEMBL10555508 | 0.87 | ACHE (0.58) | ACHEMAOBGAADRD2DRD4 | |
| SCHEMBL1607526 | 0.87 | MAOB (0.48) | MAOBKDM4ELMNAALDH1A1 | |
| SCHEMBL13645864 | 0.83 | DRD2 (0.50) | ACHEMAOBGAADRD2DRD4 | |
| SCHEMBL12463 | 0.82 | ACHE (0.57) | ACHEMAOBDRD2DRD4DRD3 | |
| SCHEMBL17561648 | 0.82 | DRD2 (0.63) | ACHEMAOBGAADRD2DRD4 | |
| SCHEMBL2047854 | 0.81 | MAOB (0.58) | ACHEMAOBKDM4ELMNAALDH1A1 | |
| SCHEMBL30114007 | 0.81 | MAOB (0.58) | ACHEMAOBKDM4ELMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10562858-B2 | Crystalline anti-trichophyton agents and preparation process thereof | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2020-02-18 | — | — | US | disclosed |
| CN-106573892-B | Crystalline anti-tinea alba bacteria medicine and preparation method thereof | 明治制果药业株式会社 | 2019-10-25 | — | — | CN | disclosed |
| CN-110218187-A | Crystallinity tinea alba fungi resisting medicine and preparation method thereof | 明治制果药业株式会社 | 2019-09-10 | — | — | CN | disclosed |
| EP-2885297-B1 | TRISUBSTITUTED PYRIDO[3,2-D]PYRIMIDINES, THEIR PREPARATION PROCESS AND THEIR THERAPEUTICAL USES | CENTRE NAT DE LA RECH SCIENT (C N R S ) (FR) | 2017-10-11 | — | — | EP | disclosed |
| US-20170233346-A1 | CRYSTALLINE ANTI-TRICHOPHYTON AGENTS AND PREPARATION PROCESS THEREOF | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2017-08-17 | — | — | US | disclosed |
| EP-3190105-A1 | CRYSTALLINE ANTI-TRICHOPHYTON DRUG AND METHOD FOR PRODUCING SAME | Meiji Seika Pharma Co., Ltd. (JP) | 2017-07-12 | — | — | EP | disclosed |
| CN-106573892-A | Crystalline anti-tinea alba bacteria medicine and preparation method thereof | 明治制果药业株式会社 | 2017-04-19 | — | — | CN | disclosed |
| CN-104203946-B | Immunologically useful arginine salts | 诺华股份有限公司 | 2017-03-22 | — | — | CN | disclosed |
| US-9449732-B2 | Charge transport film, method for producing the same, and light-emitting element and photoelectric conversion element using the same | FUJIFILM CORPORATION (JP) | 2016-09-20 | — | — | US | disclosed |
| US-9346790-B2 | Hydantoin derivatives useful as Kv3 inhibitors | AUTIFONY THERAPEUTICS LIMITED (GB) | 2016-05-24 | — | — | US | disclosed |
| US-20070010515-A1 | [1,2,4] Triazolo [1,5, a] pyrimidin-2-ylurea derivative and use thereof | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2007-01-11 | — | — | US | disclosed |
| US-20070010515-A1 | [1,2,4] Triazolo [1,5, a] pyrimidin-2-ylurea derivative and use thereof | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2007-01-11 | — | — | US | disclosed |
| WO-2004069823-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE, INC. (CA) | 2004-08-19 | — | — | WO | disclosed |
| US-6642230-B2 | Administering novel compounds which bind to corticotropin releasing factor receptors, thereby altering anxiogenic effects of CRF secretion | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2003-11-04 | — | — | US | disclosed |
| US-20030114468-A1 | Imidazopyrimidines and imidazopyridines for the treatment of neurological disorders | WILDE RICHARD GERALD (US) | 2003-06-19 | — | — | US | disclosed |
| US-6362180-B1 | ANTAGONIST TO CORTICOTROPIN RELEASING FACTOR | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2002-03-26 | — | — | US | disclosed |
| US-6143743-A | TREATMENT OF NERVOUS SYSTEM DISORDERS | DUPONT PHARMACEUTICALS COMPANY (US) | 2000-11-07 | — | — | US | disclosed |
| CN-1268137-A | Imidazopyrimidines and imidazopyridines for the treatment of neurological disorders | DU PONT PHARM CO (US) | 2000-09-27 | — | — | CN | disclosed |
| EP-0994877-A1 | IMIDAZOPYRIMIDINES AND IMIDAZOPYRIDINES FOR THE TREATMENT OF NEUROLOGICAL DISORDERS | Du Pont Pharmaceuticals Company (US) | 2000-04-26 | — | — | EP | disclosed |
| WO-1999001454-A1 | IMIDAZOPYRIMIDINES AND IMIDAZOPYRIDINES FOR THE TREATMENT OF NEUROLOGICAL DISORDERS | DU PONT PHARMACEUTICALS COMPANY (US) | 1999-01-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070010515-A1 | [1,2,4] Triazolo [1,5, a] pyrimidin-2-ylurea derivative and use thereof | HLA-C, TPMT, TAP1 | ACHE 4424/4885MAOB 3803/4885GAA 1151/4885 |
| US-20030114468-A1 | Imidazopyrimidines and imidazopyridines for the treatment of neurological disorders | CRH, CRHR1, CRHR2 | ACHE 2045/4885MAOB 2132/4885GAA 3225/4885 |
| US-10562858-B2 | Crystalline anti-trichophyton agents and preparation process thereof | ZP1, TBKBP1, MITF | ACHE 4734/4885MAOB 2978/4885GAA 1363/4885 |
| US-20170233346-A1 | CRYSTALLINE ANTI-TRICHOPHYTON AGENTS AND PREPARATION PROCESS THEREOF | ZP1, TBKBP1, MITF | ACHE 4734/4885MAOB 2978/4885GAA 1363/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.