SCHEMBL7612153

SCHEMBL7612153

CCCC(NC(=O)c1cccc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)c1)c1ccc(OC)cc1

nearest known ligand 0.54

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MTTP P55157 17/20 0.54
RXFP1 Q9HBX9 2/20 0.50
KDM4E B2RXH2 1/20 0.48
GAA P10253 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7038361 0.85 MTTP (0.48) MTTPGAA
SCHEMBL7610477 0.85 MTTP (0.53) MTTPRXFP1KDM4EGAA
SCHEMBL7609278 0.78 ALDH1A1 (0.58) MTTPRXFP1
SCHEMBL7605815 0.76 APOB (0.63) MTTPRXFP1
SCHEMBL7610756 0.75 APOB (0.51) MTTPRXFP1KDM4E
SCHEMBL7605543 0.75 F3 (0.49) MTTP
SCHEMBL7605547 0.75 F3 (0.53) MTTP
SCHEMBL7611241 0.75 MTTP (0.55) MTTP
SCHEMBL6799012 0.74 APOB (0.66) MTTPRXFP1
SCHEMBL7605511 0.74 APOB (0.56) MTTPRXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020032238-A1 Biphenylcarboxylic acid amides, the preparation thereof and the use thereof as medicaments BOEHRINGER INGELHEIM PHARMA KG (DE) 2002-03-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020032238-A1 Biphenylcarboxylic acid amides, the preparation thereof and the use thereof as medicaments MTTP, CETP, FABP1 MTTP 1/4885RXFP1 2727/4885KDM4E 1707/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.