Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5731346 | 0.80 | TSHR (0.41) | TSHRALDH1A1CYP2D6LMNAMEN1 | |
| SCHEMBL4889913 | 0.77 | LMNA (0.48) | TSHRALDH1A1CYP2D6LMNAMEN1 | |
| SCHEMBL27263148 | 0.75 | CYP2D6 (0.42) | TSHRALDH1A1CYP2D6LMNAMEN1 | |
| SCHEMBL8068587 | 0.74 | CYP2D6 (0.39) | TSHRALDH1A1CYP2D6LMNAMEN1 | |
| SCHEMBL14003863 | 0.74 | MAPK1 (0.42) | TSHRALDH1A1CYP2D6LMNAMEN1 | |
| SCHEMBL10679246 | 0.72 | TSHR (0.42) | TSHRALDH1A1CYP2D6LMNAMEN1 | |
| SCHEMBL14688891 | 0.70 | PTPN1 (0.37) | TSHRALDH1A1CYP2D6LMNAMEN1 | |
| SCHEMBL30825836 | 0.70 | TSHR (0.42) | TSHRALDH1A1CYP2D6LMNAMEN1 | |
| SCHEMBL30825821 | 0.70 | TSHR (0.42) | TSHRALDH1A1CYP2D6LMNAMEN1 | |
| SCHEMBL10675379 | 0.68 | L3MBTL1 (0.53) | TSHRCYP2D6LMNAMEN1HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023182941-A2 | A POLYMERIZABLE COMPOSITION, A THREE-DIMENSIONAL PRINTED ARTICLE AND METHODS OF PREPARING THE SAME | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2023-09-28 | — | — | WO | claimed |
| CN-113501692-A | Light heat-insulating concrete | 抚州市正兴混凝土有限公司 | 2021-10-15 | — | — | CN | claimed |
| US-7038062-B2 | Synthesis of cyclic trithiocarbonates from epoxides | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2006-05-02 | — | — | US | claimed |
| US-20060004210-A1 | SYNTHESIS OF CYCLIC TRITHIOCARBONATES FROM EPOXIDES | GOODYEAR TIRE & RUBBER COMPANY, THE | 2006-01-05 | — | — | US | claimed |
| WO-2023182941-A2 | A POLYMERIZABLE COMPOSITION, A THREE-DIMENSIONAL PRINTED ARTICLE AND METHODS OF PREPARING THE SAME | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2023-09-28 | — | — | WO | disclosed |
| US-11289238-B2 | Compositions for the filling of high aspect ratio vertical interconnect access (VIA) holes | HERAEUS PRECIOUS METALS NORTH AMERICA CONSHOHOCKEN LLC (US) | 2022-03-29 | — | — | US | disclosed |
| CN-110049977-B | Lactam, cyclic urea and carbamate and triazolone derivatives as potent and selective ROCK inhibitors | 百时美施贵宝公司 | 2022-01-18 | — | — | CN | disclosed |
| CN-113501692-A | Light heat-insulating concrete | 抚州市正兴混凝土有限公司 | 2021-10-15 | — | — | CN | disclosed |
| US-20210174983-A1 | COMPOSITIONS FOR THE FILLING OF HIGH ASPECT RATIO VERTICAL INTERCONNECT ACCESS (VIA) HOLES | HERAEUS PRECIOUS METALS NORTH AMERICA CONSHOHOCKEN LLC | 2021-06-10 | — | — | US | disclosed |
| US-10730858-B2 | Lactam, cyclic urea and carbamate, and triazolone derivatives as potent and selective rock inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2020-08-04 | — | — | US | disclosed |
| EP-3481816-B1 | LACTAM, CYCLIC UREA AND CARBAMATE, AND TRIAZOLONE DERIVATIVES AS POTENT AND SELECTIVE ROCK INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2020-06-24 | — | — | EP | disclosed |
| WO-2020031836-A1 | POLYMERIZABLE IONIC LIQUID, POLYMER, CURABLE COMPOSITION, ELECTROCHEMICAL ELEMENT MATERIAL, AND ANTISTATIC MATERIAL | セントラル硝子株式会社 | 2020-02-13 | — | — | WO | disclosed |
| US-20070135631-A1 | HETEROCYCLIC CETP INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2007-06-14 | — | — | US | disclosed |
| US-20070135631-A1 | HETEROCYCLIC CETP INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2007-06-14 | — | — | US | disclosed |
| US-20070135631-A1 | HETEROCYCLIC CETP INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2007-06-14 | — | — | US | disclosed |
| WO-2007062314-A2 | HETEROCYCLIC CETP INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-05-31 | — | — | WO | disclosed |
| WO-2007062314-A2 | HETEROCYCLIC CETP INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-05-31 | — | — | WO | disclosed |
| WO-2007062308-A2 | HOMO- AND HETEROCYCLIC COMPOUNDS SUITABLE AS CETP INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-05-31 | — | — | WO | disclosed |
| US-7038062-B2 | Synthesis of cyclic trithiocarbonates from epoxides | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2006-05-02 | — | — | US | disclosed |
| US-20060004210-A1 | SYNTHESIS OF CYCLIC TRITHIOCARBONATES FROM EPOXIDES | GOODYEAR TIRE & RUBBER COMPANY, THE | 2006-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135631-A1 | HETEROCYCLIC CETP INHIBITORS | CETP, CES1, NPC1 | TSHR 2250/4885ALDH1A1 2353/4885CYP2D6 993/4885 |
| US-20060004210-A1 | SYNTHESIS OF CYCLIC TRITHIOCARBONATES FROM EPOXIDES | TST, CXCR6, CCR6 | TSHR 925/4885ALDH1A1 3142/4885CYP2D6 433/4885 |
| US-10730858-B2 | Lactam, cyclic urea and carbamate, and triazolone derivatives as potent and selective rock inhibitors | MYLK, ROCK1, MYLK2 | TSHR 2273/4885ALDH1A1 3629/4885CYP2D6 4069/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.