Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 5/20 | 0.35 |
| ▸ | NOS1 | P29475 | 4/20 | 0.35 |
| ▸ | NOS3 | P29474 | 2/20 | 0.35 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7613926 | 0.67 | ALDH1A1 (0.36) | ALDH1A1CYP1A2CYP3A4CYP2D6MAPT | |
| SCHEMBL10768056 | 0.64 | KDM4E (0.40) | ALDH1A1ADORA3NUDT1GAAL3MBTL1 | |
| SCHEMBL10990597 | 0.62 | HPGD (0.48) | ALDH1A1CYP1A2CYP3A4MAPTGAA | |
| SCHEMBL11800949 | 0.61 | L3MBTL1 (0.46) | ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL4866608 | 0.61 | MEN1 (0.37) | ALDH1A1MAPTSMN1; SMN2L3MBTL1HPGD | |
| SCHEMBL27516313 | 0.61 | RAB9A (0.61) | ALDH1A1CYP1A2CYP3A4MAPTMAPK1 | |
| SCHEMBL10560583 | 0.60 | ADORA3 (0.35) | ALDH1A1ADORA3NOS2NOS1NOS3 | |
| SCHEMBL23674700 | 0.60 | NUDT1 (0.51) | ALDH1A1CYP1A2MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL10268206 | 0.59 | MEN1 (0.66) | ALDH1A1CYP1A2CYP3A4CYP2D6MAPT | |
| SCHEMBL10798303 | 0.59 | ALDH1A1 (0.59) | ALDH1A1CYP1A2CYP3A4CYP2D6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1232166-A2 | SYNTHESIS OF 2'-DEOXY-L-NUCLEOSIDES | Pharmasset Limited (US) | 2002-08-21 | — | — | EP | disclosed |
| WO-2001034618-A2 | SYNTHESIS OF 2'-DEOXY-L-NUCLEOSIDES | PHARMASSET LIMITED (US) | 2001-05-17 | — | — | WO | disclosed |