SCHEMBL7614769

SCHEMBL7614769

COC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCSC)NC=O

nearest known ligand 0.60

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FPR1 P21462 4/20 0.60
FPR2 P25090 4/20 0.60
ALDH1A1 P00352 1/20 0.52
THRB P10828 1/20 0.52
CYP2C9 P11712 1/20 0.52
CYP2C19 P33261 1/20 0.52
HSD17B10 Q99714 1/20 0.52
MME P08473 1/20 0.51
ANPEP P15144 1/20 0.51
BIRC2 Q13490 1/20 0.50
CAPN1 P07384 1/20 0.50
IL1RN P18510 2/20 0.49
ERAP2 Q6P179 2/20 0.49
ERAP1 Q9NZ08 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16557520 0.93 MME (0.55) FPR1FPR2ALDH1A1THRBCYP2C9
N-Formylmethionyl-Leucylphenylalanine SCHEMBL7127847 0.91 FPR1 (0.61) FPR1FPR2MME
N-Formylmethionyl-Leucylphenylalanine SCHEMBL17202476 0.91 FPR1 (0.61) FPR1FPR2MME
N-Formylmethionyl-Leucylphenylalanine SCHEMBL9903983 0.91 FPR1 (0.61) FPR1FPR2MME
N-Formylmethionyl-Leucylphenylalanine SCHEMBL39529 0.91 FPR1 (0.61) FPR1FPR2MME
N-Formylmethionyl-Leucylphenylalanine SCHEMBL4969844 0.91 FPR1 (0.61) FPR1FPR2MME
N-Formylmethionyl-Leucylphenylalanine SCHEMBL39528 0.91 FPR1 (0.61) FPR1FPR2MME
N-Formylmethionyl-Leucylphenylalanine SCHEMBL4592799 0.91 FPR1 (0.61) FPR1FPR2MME
SCHEMBL2413701 0.90 FPR1 (0.60) FPR1FPR2MME
SCHEMBL14391740 0.90 FPR1 (0.60) FPR1FPR2MMEANPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020042403-A1 Use of vitamin D analogs to treat conditions related to increased oxidative stress SERBINOVA ELENA A (US) 2002-04-11 US disclosed
US-6262041-B1 TOPICALLY ADMINISTERING THE COMPOUND 26, 27-HEXAFLUORO-1,25-DIHYDROXY VITAMIN D3 TO THE SKIN BERTEK PHARMACEUTICALS, INC. 2001-07-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020042403-A1 Use of vitamin D analogs to treat conditions related to increased oxidative stress VDR, CYP24A1, CYP2R1 FPR1 218/4885FPR2 301/4885ALDH1A1 256/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.