Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19146906 | 0.94 | LMNA (0.38) | LMNACA12CA1CA2CA3 | |
| SCHEMBL23343657 | 0.83 | LMNA (0.47) | LMNACA12CA1CA2CA3 | |
| SCHEMBL11478534 | 0.82 | LMNA (0.49) | LMNACA12CA1CA2CA3 | |
| SCHEMBL9397107 | 0.78 | TSHR (0.47) | LMNACA12CA1CA2CA3 | |
| SCHEMBL19146573 | 0.76 | LMNA (0.41) | LMNACA12CA1CA2CA3 | |
| SCHEMBL295308 | 0.75 | TGFBR1 (0.33) | RXFP1CHRM5CHRM3TGFBR1 | |
| Methacrylic Acid SCHEMBL1817343 | 0.74 | LMNA (0.45) | LMNACA12CA1CA2CA3 | |
| SCHEMBL22562961 | 0.74 | LMNA (0.42) | LMNACA12CA1CA2CA3 | |
| SCHEMBL4154528 | 0.73 | LMNA (0.44) | LMNACA12CA1CA2CA3 | |
| SCHEMBL22847870 | 0.73 | MAPT (0.37) | LMNAKMT2ATGFBR1TSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037930-A | Heterocyclic quaternized nitrogen-containing cellulosic graft polymers | GAF CHEMICALS CORPORATION (US) | 1991-08-06 | — | — | US | claimed |
| US-11912831-B2 | Hydroxyethylpyrrolidone ethacrylate/glycidyl ethacrylate copolymers | ISP INVESTMENTS LLC (US) | 2024-02-27 | — | — | US | disclosed |
| US-11912831-B2 | Hydroxyethylpyrrolidone ethacrylate/glycidyl ethacrylate copolymers | ISP INVESTMENTS LLC (US) | 2024-02-27 | — | — | US | disclosed |
| US-11859029-B2 | Methods of synthesis of homopolymers and non-homopolymers comprising repeating units derived from monomers comprising lactam and acryloyl moieties in an aqueous medium | ISP INVESTMENTS LLC (US) | 2024-01-02 | — | — | US | disclosed |
| US-11859029-B2 | Methods of synthesis of homopolymers and non-homopolymers comprising repeating units derived from monomers comprising lactam and acryloyl moieties in an aqueous medium | ISP INVESTMENTS LLC (US) | 2024-01-02 | — | — | US | disclosed |
| US-11001751-B2 | Crosslinked polymers derived from monomers having acryloyl and lactam moieties and sulfonic acid/sulfonate comonomers, compositions thereof, and applications thereof | HERCULES LLC (US) | 2021-05-11 | — | — | US | disclosed |
| US-20200407470-A1 | METHODS OF SYNTHESIS OF HOMOPOLYMERS AND NON-HOMOPOLYMERS COMPRISING REPEATING UNITS DERIVED FROM MONOMERS COMPRISING LACTAM AND ACRYLOYL MOIETIES IN AN AQUEOUS MEDIUM | ISP INVESTMENTS LLC (US) | 2020-12-31 | — | — | US | disclosed |
| US-10876015-B2 | Coating compositions for forming toner coatings | ISP INVESTMENTS LLC (US) | 2020-12-29 | — | — | US | disclosed |
| US-10865264-B2 | Hydroxyethylpyrrolidone methacrylate/glycidyl methacrylate copolymers | ISP INVESTMENTS LLC (US) | 2020-12-15 | — | — | US | disclosed |
| US-10844154-B2 | Proliferous copolymers comprising lactamic moieties | ISP INVESTMENTS LLC (US) | 2020-11-24 | — | — | US | disclosed |
| US-10765617-B2 | Personal care compositions comprising copolymers of cationic monomers and acryloyl lactam based monomers, process for the same and method of use | ISP INVESTMENTS LLC (US) | 2020-09-08 | — | — | US | disclosed |
| US-10745502-B2 | Polymers for oral care compositions | ISP INVESTMENTS LLC (US) | 2020-08-18 | — | — | US | disclosed |
| US-10632059-B2 | Non-aqueous compositions of polymers derived from monomers having acryloyl moiety and lactam moiety and applications thereof | ISP INVESTMENTS LLC (US) | 2020-04-28 | — | — | US | disclosed |
| US-20190382519-A1 | CROSS-LINKED BLOCK COPOLYMERS COMPRISING REPEATING UNITS DERIVED FROM MONOMERS COMPRISING LACTAM AND ACRYLOYL MOIETIES, COMPOSITIONS, AND APPLICATIONS THEREOF | ISP INVESTMENTS LLC (US) | 2019-12-19 | — | — | US | disclosed |
| US-20190151224-A1 | PERSONAL CARE COMPOSITIONS COMPRISING COPOLYMERS OF CATIONIC MONOMERS AND ACRYLOYL LACTAM BASED MONOMERS, PROCESS FOR THE SAME AND METHOD OF USE | ISP INVESTMENTS LLC (US) | 2019-05-23 | — | — | US | disclosed |
| US-20190015304-A1 | BLOCK COPOLYMERS COMPRISING REPEATING UNITS DERIVED FROM MONOMERS COMPRISING LACTAM AND ACRYLOYL MOIETIES AND HYDROPHOBIC MONOMERS, COMPOSITIONS, AND APPLICATIONS THEREOF | ISP INVESTMENTS LLC (US) | 2019-01-17 | — | — | US | disclosed |
| WO-2017123572-A1 | BLOCK COPOLYMERS COMPRISING REPEATING UNITS DERIVED FROM MONOMERS COMPRISING LACTAM AND ACRYLOYL MOIETIES AND HYDROPHOBIC MONOMERS, COMPOSITIONS, AND APPLICATIONS THEREOF | ISP INVESTMENTS LLC (US) | 2017-07-20 | — | — | WO | disclosed |
| EP-0572977-B1 | Bilirubin assay using crosslinkable polymers | JOHNSON & JOHNSON CLIN DIAG (US) | 1997-08-13 | — | — | EP | disclosed |
| US-4956432-A | Hydrophilic transparent crosslinked copolymer and the method for producing thereof | CESKOSLOVENSKA AKADEMIE VED (CS) | 1990-09-11 | — | — | US | disclosed |
| EP-0345794-A2 | Hydrophilic transparent crosslinked copolymers and method for their preparation | CESKOSLOVENSKA AKADEMIE VED (CS) | 1989-12-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10745502-B2 | Polymers for oral care compositions | SMARCC1, MPO, ARID2 | LMNA 1522/4885CA12 3095/4885CA1 1595/4885 |
| US-11912831-B2 | Hydroxyethylpyrrolidone ethacrylate/glycidyl ethacrylate copolymers | MMAB, PCNA, HMBS | LMNA 2499/4885CA12 1204/4885CA1 867/4885 |
| US-10632059-B2 | Non-aqueous compositions of polymers derived from monomers having acryloyl moiety and lactam moiety and applications thereof | C9, PARG, C5 | LMNA 154/4885CA12 3093/4885CA1 2470/4885 |
| US-20190015304-A1 | BLOCK COPOLYMERS COMPRISING REPEATING UNITS DERIVED FROM MONOMERS COMPRISING LACTAM AND ACRYLOYL MOIETIES AND HYDROPHOBIC MONOMERS, COMPOSITIONS, AND APPLICATIONS THEREOF | F9, ADCY9, MMS19 | LMNA 2191/4885CA12 2531/4885CA1 3645/4885 |
| US-11001751-B2 | Crosslinked polymers derived from monomers having acryloyl and lactam moieties and sulfonic acid/sulfonate comonomers, compositions thereof, and applications thereof | CAD, STS, COASY | LMNA 1683/4885CA12 1078/4885CA1 296/4885 |
| US-10844154-B2 | Proliferous copolymers comprising lactamic moieties | PCNA, MKI67, CCNA1 | LMNA 1224/4885CA12 1456/4885CA1 1980/4885 |
| US-10765617-B2 | Personal care compositions comprising copolymers of cationic monomers and acryloyl lactam based monomers, process for the same and method of use | AADAC, KRT18, AAAS | LMNA 2031/4885CA12 1202/4885CA1 615/4885 |
| US-20190382519-A1 | CROSS-LINKED BLOCK COPOLYMERS COMPRISING REPEATING UNITS DERIVED FROM MONOMERS COMPRISING LACTAM AND ACRYLOYL MOIETIES, COMPOSITIONS, AND APPLICATIONS THEREOF | ADSL, ABHD6, APH1B | LMNA 2576/4885CA12 2511/4885CA1 4103/4885 |
| US-20190151224-A1 | PERSONAL CARE COMPOSITIONS COMPRISING COPOLYMERS OF CATIONIC MONOMERS AND ACRYLOYL LACTAM BASED MONOMERS, PROCESS FOR THE SAME AND METHOD OF USE | AADAC, KRT18, AAAS | LMNA 2031/4885CA12 1202/4885CA1 615/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.