SCHEMBL761579

SCHEMBL761579

NC(=O)[C@@H](Cc1csc2ccccc12)NC(=O)C1CCNCC1

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
F10 P00742 2/20 0.52
MTNR1A P48039 1/20 0.48
GHSR Q92847 2/20 0.47
CALCRL Q16602 4/20 0.46
TACR1 P25103 1/20 0.41
DPP4 P27487 1/20 0.41
DPP8 Q6V1X1 1/20 0.41
DPP9 Q86TI2 1/20 0.41
CYP2A6 P11509 1/20 0.41
MMP2 P08253 1/20 0.41
MMP9 P14780 1/20 0.41
MMP8 P22894 1/20 0.41
CTSL P07711 1/20 0.41
CTSS P25774 1/20 0.41
CTSK P43235 1/20 0.41
CYP3A4 P08684 2/20 0.40
CAPN1 P07384 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL760888 0.88 MMP2 (0.55) F10MTNR1AGHSRCALCRLTACR1
SCHEMBL737041 0.83 GHSR (0.70) F10MTNR1AGHSRCALCRLTACR1
SCHEMBL737028 0.83 GHSR (0.70) F10MTNR1AGHSRCALCRLTACR1
SCHEMBL14615562 0.83 GHSR (0.51) F10MTNR1AGHSRCALCRLTACR1
SCHEMBL762149 0.81 GHSR (0.49) GHSRTACR1MMP9
SCHEMBL736820 0.81 GHSR (0.49) F10MTNR1AGHSRCALCRLTACR1
SCHEMBL737999 0.80 GHSR (0.49) F10MTNR1AGHSRCALCRLTACR1
SCHEMBL761165 0.80 F10 (0.52) F10GHSRCALCRLTACR1CYP2A6
SCHEMBL762665 0.80 GHSR (0.71) F10GHSR
SCHEMBL739284 0.78 GHSR (0.63) MTNR1AGHSRCALCRLTACR1MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8138218-B2 Growth hormone secretagogues IPSEN PHARMA S.A.S. (FR) 2012-03-20 US disclosed
US-20090131478-A1 Growth Hormone Secretagogues IPSEN PHARMA S.A.S. (FR) 2009-05-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090131478-A1 Growth Hormone Secretagogues GHSR, GHRHR, GHITM F10 2410/4885MTNR1A 478/4885GHSR 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.