SCHEMBL761605

SCHEMBL761605

Cc1cc(CS)c(N)c(C)c1N

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.39
TP53 P04637 1/20 0.39
CYP3A4 P08684 1/20 0.39
TSHR P16473 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
CYP1A2 P05177 1/20 0.37
ALOX15 P16050 1/20 0.37
CASP7 P55210 1/20 0.37
HIF1A Q16665 1/20 0.37
HSD17B10 Q99714 1/20 0.37
POLB P06746 2/20 0.34
MAPT P10636 1/20 0.34
HTT P42858 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL263814 0.88 TDP1 (0.32) ALDH1A1TP53CYP3A4TSHRTDP1
SCHEMBL1334753 0.80 HTT (0.41) ALDH1A1POLBMAPTHTT
SCHEMBL261835 0.80 ALDH1A1 (0.37) ALDH1A1TP53CYP3A4TSHRTDP1
SCHEMBL31329205 0.79 ALDH1A1 (0.52) ALDH1A1TP53CYP3A4TSHRTDP1
SCHEMBL1333373 0.79 ALDH1A1 (0.52) ALDH1A1TP53CYP3A4TSHRTDP1
SCHEMBL1334951 0.77 NOS3 (0.37) ALDH1A1TP53CYP3A4TSHRTDP1
SCHEMBL3801326 0.76 SKP2 (0.37) ALDH1A1TP53CYP3A4TSHRTDP1
SCHEMBL762561 0.75 ALDH1A1 (0.33) ALDH1A1TP53CYP3A4TSHRTDP1
SCHEMBL762133 0.75
SCHEMBL262306 0.74 ALDH1A1 (0.56) ALDH1A1TP53CYP3A4TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104321357-B Use of carbodiimide-containing compositions for controlling pot life 莱茵化学莱瑙有限公司 2017-02-01 CN claimed
CN-115895412-A Battery cell coating 汉高股份有限及两合公司 2023-04-04 CN disclosed
EP-2351638-B1 PLASTIC LENS MANUFACTURING METHOD AND MANUFACTURING DEVICE HOYA CORP (JP) 2016-11-23 EP disclosed
CN-106118431-A High intensity high ferro waterproof material and preparation method thereof 上海基典防水科技有限公司 2016-11-16 CN disclosed
EP-1759824-B1 METHOD OF MANUFACTURING PLASTIC LENSES HOYA CORP (JP) 2016-03-09 EP disclosed
US-20150259509-A1 TRANSPARENT MOLDED ARTICLE, OPTICAL MEMBER, PLASTIC LENS, AND METHODS OF MANUFACTURING SAME HOYA CORPORATION (JP) 2015-09-17 US disclosed
CN-101648421-B Method of manufacturing plastic lens, gasket for molding plastic lens, casting mold for molding plastic lens, casting jig for plastic lens starting material liquid, holding member for plastic lens cas HOYA CORPORATION (JP) 2014-10-15 CN disclosed
US-8377345-B2 Method of manufacturing optical member, method of manufacturing plastic lens, gasket for molding plastic lens, and jog for casting monomer HOYA CORPORATION (JP) 2013-02-19 US disclosed
US-8372317-B2 Method of casting plastic lens starting material liquid and casting apparatus and method of manufacturing plastic lens HOYA CORPORATION (JP) 2013-02-12 US disclosed
US-8138273-B2 Compositions including a polythioether PRC DeSoto International, Inc (US) 2012-03-20 US disclosed
US-20100032852-A1 METHOD OF CASTING PLASTIC LENS STARTING MATERIAL LIQUID AND CASTING APPARATUS, AND METHOD OF MANUFACTURING PLASTIC LENS HOYA CORPORATION (JP) 2010-02-11 US disclosed
EP-2133187-A1 METHOD AND DEVICE FOR POURING PLASTIC LENS MATERIAL LIQUID AND METHOD OF PRODUCING PLASTIC LENS Hoya Corporation (JP) 2009-12-16 EP disclosed
EP-1384736-B1 TRANSPARENT MOLDED OBJECTS, OPTICAL MEMBER, PLASTIC LENS, AND PROCESSES FOR PRODUCING THESE HOYA CORP (JP) 2009-08-12 EP disclosed
US-20080029914-A1 Method of manufacturing plastic lens, gasket for molding plastic lens, casting mold for molding plastic lens, casting jig for plastic lens starting material liquid, holding member for plastic lens casting mold, and plastic lens manufacturing apparatus HOYA CORPORATION (JP) 2008-02-07 US disclosed
US-20080018005-A1 Method Of Manufacturing Plastic Lens, Gasket For Molding Plastic Lens, Casting Mold For Molding Plastic Lens, Casting Jig For Plastic Lens Starting Material Liquid, Holding Member For Plastic Lens Casting Mold, And Plastic Lens Manufacturing Apparatus HOYA CORPORATION 2008-01-24 US disclosed
EP-1759824-A1 PROCESSES FOR PRODUCTION OF PLASTIC LENSES, GASKET FOR MOLDING PLASTIC LENSES, MOLDS FOR MOLDING PLASTIC LENSES, INJECTION JIG FOR THE RAW MATERIAL FLUID OF PLASTIC LENSES, HOLDING FIXTURE FOR THE MOLDS FOR PLASTIC LENSES, AND PRODUCTION UNIT FOR PLASTIC LENSES HOYA CORPORATION (JP) 2007-03-07 EP disclosed
US-20060155093-A1 Polyol compound, transparent molded article and method of manufacturing transparent molded article HOYA CORPORATION (JP) 2006-07-13 US disclosed
EP-1640394-A1 POLYOL COMPOUND, TRANSPARENT MOLDED OBJECTS, AND PROCESS FOR PRODUCING TRANSPARENT MOLDED OBJECT HOYA CORPORATION (JP) 2006-03-29 EP disclosed
US-20050200033-A1 Process for producing optical member, process for producing plastic lens, gasket for plastic lens molding, and jig for monomer injection HOYA CORPORATION (JP) 2005-09-15 US disclosed
EP-1504869-A1 PROCESS FOR PRODUCING OPTICAL MEMBER, PROCESS FOR PRODUCING PLASTIC LENS, GASKET FOR PLASTIC LENS MOLDING, AND JIG FOR MONOMER INJECTION HOYA CORPORATION (JP) 2005-02-09 EP disclosed