SCHEMBL261835

SCHEMBL261835

Cc1cc(CS)c(N)c(CS)c1N

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.37
TP53 P04637 1/20 0.37
CYP3A4 P08684 1/20 0.37
TSHR P16473 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
CYP1A2 P05177 1/20 0.35
ALOX15 P16050 1/20 0.35
CASP7 P55210 1/20 0.35
HIF1A Q16665 1/20 0.35
HSD17B10 Q99714 1/20 0.35
POLB P06746 1/20 0.32
MAPT P10636 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1334951 0.88 NOS3 (0.37) ALDH1A1TP53CYP3A4TSHRTDP1
SCHEMBL1334762 0.88 ALDH1A1 (0.42) ALDH1A1TP53CYP3A4TSHRTDP1
SCHEMBL1333756 0.86 ALDH1A1 (0.43) ALDH1A1TP53CYP3A4TSHRTDP1
SCHEMBL2724396 0.84 NOS2 (0.37) ALDH1A1TP53CYP3A4TSHRTDP1
SCHEMBL1334766 0.84 MAPT (0.33) TDP1MAPT
SCHEMBL761605 0.80 ALDH1A1 (0.39) ALDH1A1TP53CYP3A4TSHRTDP1
SCHEMBL1334943 0.78 HTT (0.39) ALDH1A1POLBMAPTHTT
SCHEMBL6129163 0.75 ALDH1A1 (0.34) ALDH1A1TP53CYP3A4TSHRTDP1
SCHEMBL2724543 0.74 IDO1 (0.39) ALDH1A1CYP3A4
SCHEMBL762561 0.74 ALDH1A1 (0.33) ALDH1A1TP53CYP3A4TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1943283-B1 POLYURETHANE-UREA ELASTOMERS BAYER MATERIALSCIENCE LLC (US) 2015-04-08 EP claimed
EP-1943283-A1 POLYURETHANE-UREA ELASTOMERS Bayer MaterialScience LLC (US) 2008-07-16 EP claimed
WO-2007050542-A1 POLYURETHANE-UREA ELASTOMERS BAYER MATERIALSCIENCE LLC (US) 2007-05-03 WO claimed
US-20070100112-A1 Polyurethane-urea elastomers BAYER MATERIALSCIENCE LLC 2007-05-03 US claimed
US-7071282-B2 Benzimidazole diamine-based polyetherimide compositions and methods for making them GENERAL ELECTRIC COMPANY (US) 2006-07-04 US claimed
EP-1633802-A1 BENZIMIDAZOLE DIAMINE-BASED POLYETHERIMIDE COMPOSITIONS AND METHODS FOR MAKING THEM GENERAL ELECTRIC COMPANY (US) 2006-03-15 EP claimed
WO-2004108797-A1 BENZIMIDAZOLE DIAMINE-BASED POLYETHERIMIDE COMPOSITIONS AND METHODS FOR MAKING THEM GENERAL ELECTRIC COMPANY (US) 2004-12-16 WO claimed
US-20040249117-A1 Benzimidazole diamine-based polyetherimide compositions and methods for making them GENERAL ELECTRIC COMPANY 2004-12-09 US claimed
US-11566145-B2 Polyurethane coating compositions and their use as gel coats COVESTRO LLC (US) 2023-01-31 US disclosed
EP-3938416-A1 POLYURETHANE COATING COMPOSITIONS AND THEIR USE AS GEL COATS Covestro LLC (US) 2022-01-19 EP disclosed
CN-113490700-A Polyurethane coating composition and its use as gel coat 科思创有限公司 2021-10-08 CN disclosed
US-20200291260-A1 POLYURETHANE COATING COMPOSITIONS AND THEIR USE AS GEL COATS COVESTRO LLC 2020-09-17 US disclosed
WO-2020185995-A1 POLYURETHANE COATING COMPOSITIONS AND THEIR USE AS GEL COATS COVESTRO LLC (US) 2020-09-17 WO disclosed
EP-3521909-A1 METHOD FOR MANUFACTURING SPECTACLE LENS, AND SPECTACLE LENS Hoya Lens Thailand Ltd. (TH) 2019-08-07 EP disclosed
WO-2004108797-A1 BENZIMIDAZOLE DIAMINE-BASED POLYETHERIMIDE COMPOSITIONS AND METHODS FOR MAKING THEM GENERAL ELECTRIC COMPANY (US) 2004-12-16 WO disclosed
US-20040249117-A1 Benzimidazole diamine-based polyetherimide compositions and methods for making them GENERAL ELECTRIC COMPANY 2004-12-09 US disclosed
US-20040151915-A1 Transparent molded objects, optical member, plastic lens, and processes for producing these HOYA CORPORATION (JP) 2004-08-05 US disclosed
EP-1384736-A1 TRANSPARENT MOLDED OBJECTS, OPTICAL MEMBER, PLASTIC LENS, AND PROCESSES FOR PRODUCING THESE HOYA CORPORATION (JP) 2004-01-28 EP disclosed
US-5106943-A Molding materials; blend of trimer of polyisocyanate, epoxy compounds, and aromatic polyamine TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1992-04-21 US disclosed
EP-0421393-A2 Resin, compositions, shaped articles, and methods for manufacture Takeda Chemical Industries, Ltd. (JP) 1991-04-10 EP disclosed