Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VHL | P40337 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7623156 | 0.81 | MEN1 (0.47) | KMT2AMEN1FAAHMAPK1ALDH1A1 | |
| SCHEMBL7622600 | 0.81 | MEN1 (0.47) | KMT2AMEN1FAAHMAPK1ALDH1A1 | |
| SCHEMBL7622667 | 0.81 | MEN1 (0.47) | KMT2AMEN1FAAHMAPK1ALDH1A1 | |
| SCHEMBL17190635 | 0.67 | VHL (0.40) | VHLKMT2AMEN1FAAHMAPK1 | |
| SCHEMBL7618079 | 0.66 | TBXAS1 (0.41) | FAAHHDAC4HDAC6 | |
| SCHEMBL22901902 | 0.66 | ALDH1A1 (0.56) | KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL12376735 | 0.64 | ALDH1A1 (0.62) | KMT2AMEN1ALDH1A1LMNAKDM4E | |
| SCHEMBL24328031 | 0.62 | VHL (0.42) | VHLALDH1A1LMNAKDM4EHDAC4 | |
| SCHEMBL3009276 | 0.62 | VHL (0.42) | VHLKMT2AMEN1MAPK1ALDH1A1 | |
| SCHEMBL29199445 | 0.62 | VHL (0.45) | VHLMAPK1ALDH1A1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1232166-A2 | SYNTHESIS OF 2'-DEOXY-L-NUCLEOSIDES | Pharmasset Limited (US) | 2002-08-21 | — | — | EP | disclosed |
| WO-2001034618-A2 | SYNTHESIS OF 2'-DEOXY-L-NUCLEOSIDES | PHARMASSET LIMITED (US) | 2001-05-17 | — | — | WO | disclosed |