Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | HTR7 | P34969 | 2/20 | 0.34 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.34 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7157403 | 0.78 | PDCD1 (0.37) | ALDH1A1CYP2A6HTR1AHTR7CA12 | |
| SCHEMBL8575892 | 0.75 | ENPP3 (0.34) | ALDH1A1CYP2A6DHFRMAOAMAOB | |
| SCHEMBL5860453 | 0.74 | ALDH1A1 (0.37) | ALDH1A1CYP2A6DHFRPTPN1MAOA | |
| SCHEMBL30229819 | 0.74 | ALDH1A1 (0.37) | ALDH1A1CYP2A6DHFRPTPN1MAOA | |
| SCHEMBL8338786 | 0.70 | ALDH1A1 (0.39) | ALDH1A1CYP2A6DHFRPTPN1MAOA | |
| SCHEMBL5860312 | 0.70 | CA12 (0.38) | ALDH1A1CYP2A6DHFRPTPN1MAOA | |
| SCHEMBL25302086 | 0.70 | ALDH1A1 (0.59) | ALDH1A1CYP2A6PTPN1KDM4ECA12 | |
| SCHEMBL27953 | 0.70 | ALDH1A1 (0.59) | ALDH1A1CYP2A6PTPN1KDM4ECA12 | |
| SCHEMBL29350007 | 0.70 | ALDH1A1 (0.59) | ALDH1A1CYP2A6PTPN1KDM4ECA12 | |
| SCHEMBL6077039 | 0.67 | ALDH1A1 (0.56) | ALDH1A1CYP2A6PTPN1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0834519-B1 | CATALYST FOR POLYOLEFIN PRODUCTION AND PROCESS FOR PRODUCING POLYOLEFIN | JAPAN POLYOLEFINS CO LTD (JP) | 2002-03-06 | — | — | EP | disclosed |
| US-6121182-A | A METALLOCENE CATALYST FOR POLYMERIZATION OF ISOTACTIC POLYOLEFINS WITH HIGH RIGIDITY AND HIGH MELTING POINT, USEFUL AS INDUSTRIAL MATERIAL FOR AUTOMOBILES | JAPAN POLYOLAFINS CO., LTD. (JP) | 2000-09-19 | — | — | US | disclosed |
| EP-0834519-A1 | CATALYST FOR POLYOLEFIN PRODUCTION AND PROCESS FOR PRODUCING POLYOLEFIN | Japan Polyolefins Co., Ltd. (JP) | 1998-04-08 | — | — | EP | disclosed |