Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
| ▸ | CNR2 | P34972 | 6/20 | 0.39 |
| ▸ | CNR1 | P21554 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7619389 | 0.80 | MMP2 (0.54) | MEN1KMT2AALDH1A1POLBRAB9A | |
| SCHEMBL7619395 | 0.80 | MMP2 (0.54) | MEN1KMT2AALDH1A1POLBRAB9A | |
| SCHEMBL7619393 | 0.80 | MMP2 (0.54) | MEN1KMT2AALDH1A1POLBRAB9A | |
| SCHEMBL9581723 | 0.76 | PKM (0.41) | MAPTTP53MEN1KMT2AALDH1A1 | |
| SCHEMBL9660625 | 0.75 | KCNH2 (0.50) | MAPTTP53MEN1KMT2AALDH1A1 | |
| SCHEMBL9658919 | 0.74 | GAA (0.44) | MAPTTP53MEN1KMT2AALDH1A1 | |
| SCHEMBL9350861 | 0.73 | MEN1 (0.46) | MAPTTP53MEN1KMT2AALDH1A1 | |
| SCHEMBL9797805 | 0.71 | MEN1 (0.41) | MAPTTP53MEN1KMT2AALDH1A1 | |
| SCHEMBL9661731 | 0.71 | ALDH1A1 (0.41) | MAPTTP53MEN1KMT2AALDH1A1 | |
| SCHEMBL9797197 | 0.70 | MEN1 (0.46) | MAPTTP53MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5204341-A | Treating spasmodic disorders in gastro-enterology, in gynecology, in obsteretics and in urology | ROUSSEL UCLAF (FR) | 1993-04-20 | — | — | US | disclosed |
| EP-0490765-A2 | 1-Arylsulfonyl-2-pyrrolidone-derivatives, process for their preparation, new in termediates, use for medicaments and drugs containing them | ROUSSEL-UCLAF (FR) | 1992-06-17 | — | — | EP | disclosed |