Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1435788 | 0.77 | MAPT (0.49) | GAATDP1L3MBTL1LMNATSHR | |
| SCHEMBL308320 | 0.73 | ALDH1A1 (0.52) | ALDH1A1HPGDGAATDP1L3MBTL1 | |
| SCHEMBL7743461 | 0.71 | MAPT (0.58) | ALDH1A1HPGDGAATDP1L3MBTL1 | |
| SCHEMBL8544110 | 0.70 | TDP1 (0.49) | HPGDTDP1L3MBTL1LMNATSHR | |
| SCHEMBL9447444 | 0.70 | PKM (0.61) | ALDH1A1HPGDGAAL3MBTL1LMNA | |
| SCHEMBL8189201 | 0.70 | TDP1 (0.66) | ALDH1A1HPGDGAATDP1L3MBTL1 | |
| SCHEMBL28856174 | 0.69 | CCR1 (0.47) | ALDH1A1KDM4E | |
| SCHEMBL28932912 | 0.69 | TDP1 (0.56) | TDP1L3MBTL1LMNATSHRSMN1; SMN2 | |
| SCHEMBL9372170 | 0.69 | MAPT (0.51) | TDP1L3MBTL1LMNASMN1; SMN2MEN1 | |
| SCHEMBL28856048 | 0.68 | CCR1 (0.43) | ALDH1A1HPGDLMNATSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1230248-A2 | TRANSITION METAL COMPLEXES ATTACHED TO A POLYMER VIA A FLEXIBLE CHAIN | Therasense, Inc. (US) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001036660-A2 | TRANSITION METAL COMPLEXES ATTACHED TO A POLYMER VIA A FLEXIBLE CHAIN | THERASENSE, INC. (US) | 2001-05-25 | — | — | WO | disclosed |