Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5100045 | 0.79 | MAPT (0.47) | MAPTTDP1MEN1KMT2ALMNA | |
| SCHEMBL8992699 | 0.77 | PKM (0.49) | MAPTTDP1MEN1KMT2ALMNA | |
| SCHEMBL8992759 | 0.77 | PKM (0.51) | MAPTTDP1MEN1KMT2ALMNA | |
| SCHEMBL12202119 | 0.72 | ALDH1A1 (0.68) | MAPTTDP1CYP2C19 | |
| SCHEMBL9052259 | 0.72 | PKM (0.52) | MAPTTDP1MEN1KMT2ALMNA | |
| SCHEMBL7743461 | 0.71 | MAPT (0.58) | MAPTTDP1MEN1KMT2ALMNA | |
| SCHEMBL10632392 | 0.71 | TDP1 (0.54) | MAPTTDP1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6790333 | 0.71 | TDP1 (0.71) | MAPTTDP1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4351612 | 0.71 | TDP1 (0.66) | MAPTTDP1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL22922753 | 0.70 | TSHR (0.48) | MAPTTDP1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0618907-A1 | 1-(ARYLALKYL-AMINOALKYL)IMIDAZOLE DERIVATIVES, PROCESSES OF PREPARATION AND USE AS THERAPEUTICAL AGENTS | Knoll AG (DE) | 1994-10-12 | — | — | EP | disclosed |