SCHEMBL308320

SCHEMBL308320

Cc1cccc(-c2nccn2CCCCCCN2C(=O)c3ccccc3C2=O)n1

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.52
GAA P10253 1/20 0.52
HPGD P15428 1/20 0.52
TDP1 Q9NUW8 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
MEN1 O00255 1/20 0.42
CYP1A2 P05177 1/20 0.42
CHRM2 P08172 1/20 0.42
CYP2C19 P33261 1/20 0.42
KMT2A Q03164 1/20 0.42
HTR1A P08908 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8910934 0.80 ESR1 (0.56) TDP1L3MBTL1MEN1CYP1A2CYP2C19
SCHEMBL308466 0.80 CCR1 (0.41) ALDH1A1CYP2C19KMT2A
Hydrochloric Acid SCHEMBL28865099 0.79 CCR1 (0.40) ALDH1A1CYP2C19KMT2A
SCHEMBL8443965 0.77 ESR1 (0.56) TDP1L3MBTL1MEN1CYP1A2CYP2C19
SCHEMBL3040144 0.77 ALDH1A1 (0.53) ALDH1A1KMT2A
SCHEMBL7619906 0.73 ALDH1A1 (0.51) ALDH1A1GAAHPGDTDP1L3MBTL1
SCHEMBL11094158 0.72 HTR1A (0.47) HTR1A
SCHEMBL15326986 0.72 ALDH1A1 (0.47) ALDH1A1GAAHPGDTDP1KMT2A
SCHEMBL4651613 0.71 ESR1 (0.58) HTR1A
SCHEMBL4967468 0.71 TLR8 (0.50) ALDH1A1TDP1L3MBTL1HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10219730-B2 Redox polymers ABBOTT DIABETES CARE INC. (US) 2019-03-05 US disclosed
US-20160296147-A1 Redox Polymers THERASENSE, INC. 2016-10-13 US disclosed
US-9320467-B2 Redox polymers ABBOTT DIABETES CARE INC. (US) 2016-04-26 US disclosed
US-20140364710-A1 Redox Polymers THERASENSE, INC. 2014-12-11 US disclosed
US-8828204-B2 Redox polymers ABBOTT DIABETES CARE INC. (US) 2014-09-09 US disclosed
US-8795490-B2 Redox polymers ABBOTT DIABETES CARE INC. (US) 2014-08-05 US disclosed
US-8637194-B2 Bio-nano power cells and their uses BIO-NANO POWER, LLC (US) 2014-01-28 US disclosed
US-20130330293-A1 BIO-NANO POWER CELLS AND THEIR USES BIO-NANO POWER (US) 2013-12-12 US disclosed
US-8512534-B2 Redox polymers ABBOTT DIABETES CARE INC. (US) 2013-08-20 US disclosed
US-8168052-B2 Transition metal complexes with bidentate ligand having an imidazole ring ABBOTT DIABETES CARE INC. (US) 2012-05-01 US disclosed
US-8092662-B2 Redox polymers ABBOTT DIABETES CARE INC. (US) 2012-01-10 US disclosed
US-20110306111-A1 Redox Polymers ABBOTT DIABETES CARE INC. 2011-12-15 US disclosed
US-20110303538-A1 Redox Polymers ABBOTT DIABETES CARE INC. 2011-12-15 US disclosed
US-20110303537-A1 Redox Polymers ABBOTT DIABETES CARE INC. 2011-12-15 US disclosed
US-20100288634-A1 Transition Metal Complexes with Bidentate Ligand Having an Imidazole Ring ABBOTT DIABETES CARE INC. 2010-11-18 US disclosed
EP-1230248-B1 TRANSITION METAL COMPLEXES ATTACHED TO A POLYMER VIA A FLEXIBLE CHAIN THERASENSE INC (US) 2007-06-06 EP disclosed
US-6605200-B1 Charge transfer compounds comprising polymers such as polyvinylpyridine and/or copolymers coupled to osmium compounds, used as biosensors in redox systems THERASENSE, INC. 2003-08-12 US disclosed
EP-1230248-A2 TRANSITION METAL COMPLEXES ATTACHED TO A POLYMER VIA A FLEXIBLE CHAIN Therasense, Inc. (US) 2002-08-14 EP disclosed
WO-2001036660-A2 TRANSITION METAL COMPLEXES ATTACHED TO A POLYMER VIA A FLEXIBLE CHAIN THERASENSE, INC. (US) 2001-05-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130330293-A1 BIO-NANO POWER CELLS AND THEIR USES GPX4, GPX1, LPO ALDH1A1 521/4885GAA 3418/4885HPGD 735/4885
US-10219730-B2 Redox polymers PPOX, OTC, ME3 ALDH1A1 1292/4885GAA 965/4885HPGD 165/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.