Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | DGKA | P23743 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | TOP2A | P11388 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7617346 | 0.85 | ALDH1A1 (0.36) | ALDH1A1DGKAGLATOP2ATDP1 | |
| SCHEMBL7621113 | 0.79 | CYP4F2 (0.47) | ALDH1A1DGKAMAPTTDP1MEN1 | |
| SCHEMBL7613936 | 0.79 | CYP3A4 (0.45) | ALDH1A1DGKAMAPTTDP1 | |
| SCHEMBL7623376 | 0.78 | CYP4F2 (0.46) | ALDH1A1DGKAMAPTTDP1MEN1 | |
| SCHEMBL25427885 | 0.78 | ALDH1A1 (0.42) | ALDH1A1DGKAMAPTGLATOP2A | |
| SCHEMBL7623134 | 0.70 | LMNA (0.45) | ALDH1A1MAPTKDM4EMIFGAA | |
| SCHEMBL7618333 | 0.69 | LMNA (0.47) | ALDH1A1MAPTKDM4EMIFGAA | |
| SCHEMBL33810 | 0.67 | DGKA (0.74) | ALDH1A1DGKAMAPTTDP1KDM4E | |
| SCHEMBL7621773 | 0.67 | TBXAS1 (0.61) | MAPT | |
| SCHEMBL7614088 | 0.67 | TBXAS1 (0.61) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1232166-A2 | SYNTHESIS OF 2'-DEOXY-L-NUCLEOSIDES | Pharmasset Limited (US) | 2002-08-21 | — | — | EP | disclosed |
| WO-2001034618-A2 | SYNTHESIS OF 2'-DEOXY-L-NUCLEOSIDES | PHARMASSET LIMITED (US) | 2001-05-17 | — | — | WO | disclosed |