SCHEMBL762122

SCHEMBL762122

C[Si](C)(C)c1ccc(N(c2ccc3c(-c4ccccc4-c4ccccc4)c4cc(N(c5ccc([Si](C)(C)C)cc5)c5cccc6ccccc56)ccc4c(-c4ccccc4-c4ccccc4)c3c2)c2cccc3ccccc23)cc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CRHR1 P34998 1/20 0.34
ALDH1A1 P00352 2/20 0.32
MAPT P10636 2/20 0.32
MAPK1 P28482 2/20 0.32
ATM Q13315 2/20 0.32
TDP1 Q9NUW8 2/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
KDM4E B2RXH2 1/20 0.32
TP53 P04637 1/20 0.32
HPGD P15428 1/20 0.32
TSHR P16473 1/20 0.32
NFKB1 P19838 1/20 0.32
NFKB2 Q00653 1/20 0.32
RELA Q04206 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HSD17B10 Q99714 1/20 0.32
TNF P01375 1/20 0.32
GPR84 Q9NQS5 1/20 0.31
DHFR P00374 1/20 0.31
SIGMAR1 Q99720 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL760844 0.91 DHFR (0.34) MAPTKDM4ESMN1; SMN2DHFRSIGMAR1
SCHEMBL761406 0.91 ESR1 (0.34) ALDH1A1MAPTL3MBTL1KDM4EHPGD
SCHEMBL761299 0.89 ENPP1 (0.38) ALDH1A1ATMKDM4EHSD17B10GPR84
SCHEMBL762128 0.89 ESR1 (0.33) GPR84DHFRSIGMAR1
SCHEMBL14424428 0.88 SIGMAR1 (0.34) DHFRSIGMAR1
SCHEMBL761402 0.86 PTAFR (0.32) ALDH1A1MAPTMAPK1ATMTDP1
SCHEMBL762139 0.85 ALDH1A1 (0.36) CRHR1ALDH1A1MAPTMAPK1ATM
SCHEMBL761434 0.85 PTAFR (0.33) ALDH1A1MAPTMAPK1ATMTDP1
SCHEMBL761416 0.83 DHFR (0.35) ALDH1A1MAPTMAPK1ATMTDP1
SCHEMBL14516005 0.83 DHFR (0.37) ALDH1A1MAPTMAPK1ATMTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1902013-B1 NOVEL ANTHRACENE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, AND ORGANIC ELECTRONIC LIGHT EMITTING DEVICE USING THE SAME LG CHEMICAL LTD (KR) 2016-06-01 EP disclosed
US-8137823-B2 Anthracene derivatives, process for preparation thereof, and organic electronic light emitting device using the same LG CHEM, LTD. (KR) 2012-03-20 US disclosed
US-20090079334-A1 Novel Anthracene Derivatives, Process for Preparation Thereof, and Organic Electronic Light Emitting Device Using the Same LG CHEM, LTD. (KR) 2009-03-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090079334-A1 Novel Anthracene Derivatives, Process for Preparation Thereof, and Organic Electronic Light Emitting Device Using the Same XPOT, ALAD, APRT CRHR1 4852/4885ALDH1A1 434/4885MAPT 1491/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.