SCHEMBL760844

SCHEMBL760844

C[Si](C)(C)c1ccc(N(c2ccc3c(-c4cccc5ccccc45)c4cc(N(c5ccc([Si](C)(C)C)cc5)c5cccc6ccccc56)ccc4c(-c4cccc5ccccc45)c3c2)c2cccc3ccccc23)cc1

nearest known ligand 0.34

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
DHFR P00374 2/20 0.34
SIGMAR1 Q99720 5/20 0.33
PSD A5PKW4 1/20 0.32
NPC1 O15118 1/20 0.32
MAPT P10636 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
ALOX15 P16050 1/20 0.31
KDM4E B2RXH2 2/20 0.31
C5AR1 P21730 1/20 0.31
ENPP3 O14638 1/20 0.30
ENPP1 P22413 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
KCNQ3 O43525 1/20 0.30
KCNQ2 O43526 1/20 0.30
NISCH Q9Y2I1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14516005 0.92 DHFR (0.37) DHFRPSDMAPTSMN1; SMN2ALOX15
SCHEMBL761299 0.91 ENPP1 (0.38) DHFRRAB9AKDM4EENPP3ENPP1
SCHEMBL762122 0.91 CRHR1 (0.34) DHFRSIGMAR1MAPTSMN1; SMN2KDM4E
SCHEMBL761416 0.90 DHFR (0.35) DHFRPSDMAPTSMN1; SMN2ALOX15
SCHEMBL761406 0.88 ESR1 (0.34) DHFRSIGMAR1MAPTKDM4EC5AR1
SCHEMBL13995111 0.88 DHFR (0.35) DHFRSIGMAR1NPC1MAPTRAB9A
SCHEMBL12014674 0.87 SIGMAR1 (0.38) DHFRSIGMAR1KDM4EMEN1KMT2A
SCHEMBL762139 0.87 ALDH1A1 (0.36) DHFRMAPTRAB9ASMN1; SMN2KDM4E
SCHEMBL13333650 0.86 SIGMAR1 (0.37) DHFRSIGMAR1MAPTKDM4EMEN1
SCHEMBL762128 0.86 ESR1 (0.33) DHFRSIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1902013-B1 NOVEL ANTHRACENE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, AND ORGANIC ELECTRONIC LIGHT EMITTING DEVICE USING THE SAME LG CHEMICAL LTD (KR) 2016-06-01 EP disclosed
US-8137823-B2 Anthracene derivatives, process for preparation thereof, and organic electronic light emitting device using the same LG CHEM, LTD. (KR) 2012-03-20 US disclosed
US-20090079334-A1 Novel Anthracene Derivatives, Process for Preparation Thereof, and Organic Electronic Light Emitting Device Using the Same LG CHEM, LTD. (KR) 2009-03-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090079334-A1 Novel Anthracene Derivatives, Process for Preparation Thereof, and Organic Electronic Light Emitting Device Using the Same XPOT, ALAD, APRT DHFR 3494/4885SIGMAR1 3640/4885PSD 3298/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.