Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | BCL2 | P10415 | 1/20 | 0.37 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CASP1 | P29466 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | S100A4 | P26447 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL762145 | 0.86 | HKDC1 (0.43) | HKDC1MAPK1CYP1A2CRHBPCRHR2 | |
| SCHEMBL26462014 | 0.86 | HKDC1 (0.43) | HKDC1MAPK1CYP1A2CRHBPCRHR2 | |
| SCHEMBL14038369 | 0.84 | PTPRC (0.39) | PTPRCBCL2HKDC1MAPK1CYP1A2 | |
| SCHEMBL28912042 | 0.83 | L3MBTL1 (0.44) | HKDC1MAPK1CRHBPCRHR2KEAP1 | |
| SCHEMBL14134081 | 0.81 | ALDH1A1 (0.52) | HKDC1MAPK1CYP1A2CRHBPCRHR2 | |
| SCHEMBL23802651 | 0.79 | CES1 (0.53) | PTPRCBCL2HKDC1MAPK1CYP1A2 | |
| SCHEMBL701595 | 0.73 | ALDH1A1 (0.35) | PTPRCHKDC1MAPK1CYP1A2CRHBP | |
| SCHEMBL29485718 | 0.72 | CYP1A2 (0.50) | PTPRCBCL2HKDC1MAPK1CYP1A2 | |
| SCHEMBL2261886 | 0.72 | CYP1A2 (0.50) | PTPRCBCL2HKDC1MAPK1CYP1A2 | |
| SCHEMBL28018791 | 0.72 | PTPRC (0.71) | PTPRCBCL2MAPK1CYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138668-B2 | Benzo[a]fluoranthene compound and organic light emitting device using the same | CANON KABUSHIKI KAISHA (JP) | 2012-03-20 | — | — | US | disclosed |
| US-20100019661-A1 | BENZO[a]FLUORANTHENE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME | CANON KABUSHIKI KAISHA (JP) | 2010-01-28 | — | — | US | disclosed |
| WO-2008140134-A1 | BENZO[A]FLUORANTHENE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME | CANON KABUSHIKI KAISHA (JP) | 2008-11-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100019661-A1 | BENZO[a]FLUORANTHENE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME | AFF1, AFF2, CYP1A1 | PTPRC 4873/4885BCL2 3542/4885HKDC1 4700/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.