Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | CASP1 | P29466 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26462014 | 1.00 | HKDC1 (0.43) | HKDC1CRHBPCRHR2KEAP1NFE2L2 | |
| SCHEMBL762147 | 0.86 | PTPRC (0.41) | HKDC1CRHBPCRHR2KEAP1NFE2L2 | |
| SCHEMBL14134081 | 0.83 | ALDH1A1 (0.52) | HKDC1CRHBPCRHR2KEAP1NFE2L2 | |
| SCHEMBL701595 | 0.82 | ALDH1A1 (0.35) | HKDC1CRHBPCRHR2KEAP1NFE2L2 | |
| SCHEMBL28912042 | 0.82 | L3MBTL1 (0.44) | HKDC1CRHBPCRHR2KEAP1NFE2L2 | |
| SCHEMBL3183695 | 0.79 | CES1 (0.54) | ALDH1A1MAPK1CASP1L3MBTL1PABPC1 | |
| SCHEMBL28517525 | 0.78 | DNMT1 (0.40) | KEAP1ALDH1A1TSHRMAPK1HSD17B10 | |
| SCHEMBL4762276 | 0.77 | CRHBP (0.50) | HKDC1CRHBPCRHR2KEAP1NFE2L2 | |
| SCHEMBL22605624 | 0.76 | TYMS (0.46) | HKDC1TSHRCES1 | |
| SCHEMBL31037900 | 0.76 | TYMS (0.46) | HKDC1TSHRCES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2160373-B1 | BENZO[a]FLUORANTHENE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME | CANON KK (JP) | 2014-05-21 | — | — | EP | disclosed |
| US-8293383-B2 | Benzo[a]fluoranthene compound and organic light emitting device using the same | CANON KABUSHIKI KAISHA (JP) | 2012-10-23 | — | — | US | disclosed |
| US-8293383-B2 | Benzo[a]fluoranthene compound and organic light emitting device using the same | CANON KABUSHIKI KAISHA (JP) | 2012-10-23 | — | — | US | disclosed |
| EP-2162414-B1 | BENZO[a]FLUORANTHENE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME | CANON KK (JP) | 2012-08-01 | — | — | EP | disclosed |
| US-8138668-B2 | Benzo[a]fluoranthene compound and organic light emitting device using the same | CANON KABUSHIKI KAISHA (JP) | 2012-03-20 | — | — | US | disclosed |
| US-8110824-B2 | Benzo[a]fluoranthene compound and organic light emitting device using the same | CANON KABUSHIKI KAISHA (JP) | 2012-02-07 | — | — | US | disclosed |
| US-8110824-B2 | Benzo[a]fluoranthene compound and organic light emitting device using the same | CANON KABUSHIKI KAISHA (JP) | 2012-02-07 | — | — | US | disclosed |
| US-20110049479-A1 | BENZO[a]FLUORANTHENE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME | CANON KABUSHIKI KAISHA (JP) | 2011-03-03 | — | — | US | disclosed |
| US-20110049479-A1 | BENZO[a]FLUORANTHENE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME | CANON KABUSHIKI KAISHA (JP) | 2011-03-03 | — | — | US | disclosed |
| US-20100237328-A1 | BENZO[a]FLUORANTHENE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME | CANON KABUSHIKI KAISHA (JP) | 2010-09-23 | — | — | US | disclosed |
| US-20100237328-A1 | BENZO[a]FLUORANTHENE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME | CANON KABUSHIKI KAISHA (JP) | 2010-09-23 | — | — | US | disclosed |
| US-20100019661-A1 | BENZO[a]FLUORANTHENE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME | CANON KABUSHIKI KAISHA (JP) | 2010-01-28 | — | — | US | disclosed |
| WO-2008140132-A1 | BENZO[A]FLUORANTHENE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME | CANON KABUSHIKI KAISHA (JP) | 2008-11-20 | — | — | WO | disclosed |
| WO-2008140133-A1 | BENZO[a]FLUORANTHENE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME | CANON KABUSHIKI KAISHA (JP) | 2008-11-20 | — | — | WO | disclosed |
| WO-2008140134-A1 | BENZO[A]FLUORANTHENE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME | CANON KABUSHIKI KAISHA (JP) | 2008-11-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110049479-A1 | BENZO[a]FLUORANTHENE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME | AFF1, CYP1A1, CYP1B1 | HKDC1 4048/4885CRHBP 4264/4885CRHR2 1913/4885 |
| US-20100237328-A1 | BENZO[a]FLUORANTHENE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME | CYP1A1, CYP1B1, AFF1 | HKDC1 4046/4885CRHBP 2753/4885CRHR2 1025/4885 |
| US-20100019661-A1 | BENZO[a]FLUORANTHENE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME | AFF1, AFF2, CYP1A1 | HKDC1 4700/4885CRHBP 4008/4885CRHR2 2530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.