Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7619282 | 0.89 | CYP2D6 (0.39) | ALDH1A1RECQLTAAR1THRBLMNA | |
| SCHEMBL7622457 | 0.87 | RECQL (0.47) | ALDH1A1RECQLTAAR1THRBMMP8 | |
| SCHEMBL7622507 | 0.85 | ALDH1A1 (0.45) | ALDH1A1RECQLTAAR1THRBATM | |
| SCHEMBL5035787 | 0.79 | ALDH1A1 (0.47) | ALDH1A1RECQLTAAR1THRBMMP8 | |
| SCHEMBL5035826 | 0.79 | ALDH1A1 (0.47) | ALDH1A1RECQLTAAR1THRBMMP8 | |
| SCHEMBL7621982 | 0.77 | ALDH1A1 (0.41) | ALDH1A1RECQLTAAR1THRBLMNA | |
| SCHEMBL7617220 | 0.77 | ALDH1A1 (0.43) | ALDH1A1RECQLTAAR1THRBLMNA | |
| SCHEMBL12733180 | 0.75 | ALDH1A1 (0.59) | ALDH1A1RECQLTAAR1THRBATM | |
| SCHEMBL7708057 | 0.74 | CYP2D6 (0.47) | POLB | |
| SCHEMBL7615568 | 0.74 | SPR (0.40) | ALDH1A1RECQLTAAR1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778263-B1 | BENZENE COMPOUND AND MEDICINAL USE THEREOF | WELFIDE CORP (JP) | 2002-01-09 | — | — | EP | disclosed |