SCHEMBL9517525

SCHEMBL9517525

C=CC(=O)OC(CC)Oc1ccc(C(C)(C)c2ccc(OC(CC)OC(=O)C(=C)C)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.36
KDM4E B2RXH2 7/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
GAA P10253 2/20 0.35
THRB P10828 2/20 0.35
AR P10275 1/20 0.34
HTT P42858 3/20 0.34
KMT2A Q03164 3/20 0.34
MEN1 O00255 2/20 0.34
POLB P06746 3/20 0.32
NPC1 O15118 1/20 0.32
MAPT P10636 1/20 0.32
RAB9A P51151 1/20 0.32
NR1H4 Q96RI1 1/20 0.32
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL959624 0.93 ALDH1A1 (0.40) ALDH1A1KDM4ESMN1; SMN2GAATHRB
SCHEMBL957304 0.91 AR (0.39) ALDH1A1KDM4ESMN1; SMN2GAAAR
SCHEMBL7625525 0.85 THRB (0.36) ALDH1A1KDM4ESMN1; SMN2GAATHRB
SCHEMBL7623767 0.84 AR (0.36) ALDH1A1KDM4ESMN1; SMN2GAAAR
SCHEMBL195096 0.82 KDM4E (0.43) ALDH1A1KDM4ESMN1; SMN2GAAAR
SCHEMBL7633691 0.81 KDM4E (0.37) ALDH1A1KDM4ESMN1; SMN2GAAAR
SCHEMBL17159499 0.81 KDM4E (0.37) ALDH1A1KDM4ESMN1; SMN2GAAAR
SCHEMBL10707002 0.80 THRB (0.36) ALDH1A1KDM4EGAATHRBKMT2A
SCHEMBL14113638 0.79 MAPT (0.43) ALDH1A1KDM4ESMN1; SMN2GAATHRB
SCHEMBL14182067 0.79 THRB (0.43) ALDH1A1KDM4ESMN1; SMN2GAATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0316507-B1 Graded index lens array MITSUBISHI RAYON CO (JP) 1993-12-15 EP disclosed
US-4852982-A RESOLUTION; ACRYLIC RESIN AND FLUORINATED ALKYL ACRYLATE MITSUBISHI RAYON CO., LTD. (JP) 1989-08-01 US disclosed