Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
| ▸ | HTT | P42858 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | AR | P10275 | 2/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL959624 | 0.92 | ALDH1A1 (0.40) | THRBKDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL9517525 | 0.85 | ALDH1A1 (0.36) | THRBKDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL7623767 | 0.84 | AR (0.36) | KDM4EALDH1A1HTTSMN1; SMN2KMT2A | |
| SCHEMBL14182067 | 0.78 | THRB (0.43) | THRBKDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL14113638 | 0.78 | MAPT (0.43) | THRBKDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL137573 | 0.77 | ALDH1A1 (0.37) | THRBKDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL5899611 | 0.76 | KMT2A (0.41) | KDM4EALDH1A1HTTSMN1; SMN2KMT2A | |
| SCHEMBL6905540 | 0.76 | ALDH1A1 (0.35) | THRBKDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL28244460 | 0.76 | THRB (0.48) | THRBKDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL2921941 | 0.76 | TSHR (0.42) | THRBALDH1A1SMN1; SMN2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5942303-A | CURABLE ADDITION TERPOLYMER BASED ON 2,2-BIS(P-(METH)ACRYLOYL -(P-(METH)ACRYLOYLOXY(ALKYLOXY)N-PHENYL)PROPANES, WHERE N IS 2-5, AND UNSATURATED COMPOUND; IMPACT STRENGTH; LOW SPECIFIC GRAVITY; LIGHTWEIGHT; EYEGLASSES; CONTACT LENSES; LENSES | NOF CORPORATION (JP) | 1999-08-24 | — | — | US | claimed |
| EP-0828167-B1 | Resin composition for polymerization casting and optical material | NOF CORP (JP) | 2002-07-03 | — | — | EP | disclosed |
| US-5942303-A | CURABLE ADDITION TERPOLYMER BASED ON 2,2-BIS(P-(METH)ACRYLOYL -(P-(METH)ACRYLOYLOXY(ALKYLOXY)N-PHENYL)PROPANES, WHERE N IS 2-5, AND UNSATURATED COMPOUND; IMPACT STRENGTH; LOW SPECIFIC GRAVITY; LIGHTWEIGHT; EYEGLASSES; CONTACT LENSES; LENSES | NOF CORPORATION (JP) | 1999-08-24 | — | — | US | disclosed |
| EP-0828167-A2 | Resin composition for polymerization casting and optical material | NOF CORPORATION (JP) | 1998-03-11 | — | — | EP | disclosed |